Publications by authors named "Khoo K"

Introduction: Medial congruent (MC) systems and Posterior stabilized (PS) systems are widely utilized as implant options in total knee arthroplasties (TKAs). Nevertheless, determining which system yields superior clinical outcomes remains unresolved. This study seeks to compare these two systems by conducting a retrospective analysis of data from a single surgeon's registry encompassing both systems.

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Microalgae are widely recognized for their capacity to generate value-added products in a variety of sectors, including the pharmaceutical and food industries, bioenergy industries and wastewater industries. The quality of a microalga is significantly influenced by its proliferation. Along with growth, the biochemical profile may also vary based on the nutrient that is supplemented.

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The escalating crisis of marine plastic waste pose threats to the marine ecosystems. Statistics revealed that a staggering 8 MMT of plastic inundates the marine atmosphere annually. This review delves into a pivotal aspect of this issue, examining the release of additives like brominated flame retardants, phthalates, and bisphenol A from plastic into the environment.

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Heavy metal contamination of water sources has long been a silent yet potent threat, endangering environmental and human health. Conventional wastewater treatments are costly due to high infrastructure expenses, energy consumption, and chemical usage. These treatments lead to secondary environmental pollution, such as producing toxic sludge, greenhouse gaseous emissions, and residual pollutants discharges.

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Gastrointestinal cell culture technology has evolved in the past decade with the integration of microfluidic technologies, bringing advantages with greater selectivity and cost effectiveness. Herein, these technologies are sorted into three categories, namely the cell-culture insert devices, conventional microfluidic devices, and 3D-printed microfluidic devices. Each category is discussed in brief with improvements also discussed here.

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Background: Global food loss and waste have raised environmental concerns regarding the generation of greenhouse gases (e.g., carbon dioxide and methane gas), which directly contribute to climate change.

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Article Synopsis
  • * A survey of 408 students was conducted, using PLS-SEM analysis to find connections between these factors and mukbang ASMR obsession, revealing that loneliness is a key determinant.
  • * The research also highlights the role of mediated voyeurism and intertemporal choice, showing how they influence the relationship between loneliness, companionship, and mukbang ASMR addiction.
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  • Hypocalcaemia is a common complication after total thyroidectomy, with a rate of 23-40% observed at UMMC, prompting a study to compare prophylactic calcium infusion vs. placebo to see if it reduces early hypocalcaemia rates.
  • Thirty-four patients were equally randomized into two groups (intervention and placebo) and results showed no significant difference in early hypocalcaemia rates or hospital stay duration, although calcium levels were slightly higher at 24 hours in the intervention group.
  • Despite finding no substantial benefits in preventing early hypocalcaemia, the study suggests further research with larger populations may be necessary to fully evaluate the effectiveness of prophylactic calcium treatment following total thyroidectomy.
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During neuronal pruning, phagocytes engulf shed cellular debris to avoid inflammation and maintain tissue homeostasis. How phagocytic receptors recognize degenerating neurites had been unclear. Here, we identify two glucosyltransferases Alg8 and Alg10 of the N-glycosylation pathway required for dendrite fragmentation and clearance through genetic screen.

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The fucosylation of glycoproteins regulates diverse physiological processes. Inhibitors that can control cellular levels of protein fucosylation have consequently emerged as being of high interest. One area where inhibitors of fucosylation have gained significant attention is in the production of afucosylated antibodies, which exhibit superior antibody-dependent cell cytotoxicity as compared to their fucosylated counterparts.

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Frequent detection of terbutaline in wastewater highlights its potential risks to human health associated in the environment. Exposure to terbutaline through contaminated water sources or food chain have adverse effects to human health. This work emphasized on the removal of terbutaline from wastewater using adsorption technology.

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Introduction: Cemented hip hemiarthroplasty is a routine surgical option for elderly neck of femur (NOF) fractures. It is uncertain if quality of cementing has any effect on functional outcomes. The aim of this study was to determine if the quality of cementing would affect short term functional outcomes in elderly neck of femur fractures.

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Dyes are the most ubiquitous organic pollutants in industrial effluents. They are highly toxic to both plants and animals; thus, their removal is paramount to the sustainability of ecosystem. However, they have shown resistance to photolysis and various biological, physical, and chemical wastewater remediation processes.

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In the pursuit of alternatives for conventional diesel, sourced from non-renewable fossil fuel, biodiesel has gained attentions for its intrinsic benefits. However, the commercial production process for biodiesel is still not sufficiently competitive. This review analyses microalgal lipid, one of the important sources of biodiesel, and its cultivation techniques with recent developments in the technical aspects.

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Even though researches have shown that biochar can improve soil-health and plant-growth even in harsh environments and get rid of harmful heavy metals and new contaminants, it is still not sustainable, affordable, or effective enough. Therefore, scientists are required to develop nanomaterials in order to preserve numerous aquatic and terrestrial species. The carbonaceous chemical known as nano-biochar (N-BC) can be used to get rid of metal contamination and emerging contaminants.

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Introduction: Three-dimensional (3D) printed models may help patients understand complex anatomic pathologies such as femoroacetabular impingement syndrome (FAIS). We aimed to assess patient understanding and satisfaction when using 3D printed models compared with standard imaging modalities for discussion of FAIS diagnosis and surgical plan.

Methods: A consecutive series of 76 new patients with FAIS (37 patients in the 3D model cohort and 39 in the control cohort) from a single surgeon's clinic were educated using imaging and representative 3D printed models of FAI or imaging without models (control).

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Environmental pollution has been increasing since last decade due to increasing industrialisation and urbanisation. Various kinds ofenvironmental pollutants including carbon dioxide (CO), dyes, pharmaceuticals, phenols, heavy metals along with many organic and inorganic species have been discovered in the various environmental compartments which possess harmful impacts tox human health, wildlife, and ecosystems. Thus, various efforts have been made through regulations, technological advancements, and public awareness campaigns to reduce the impact of the pollution.

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Background: When treating chronic prosthetic joint infection after shoulder arthroplasty, removal of the implants and cement is typically pursued because they represent a potential nidus for infection. However, complete removal can increase morbidity and compromise bone stock that is important for achieving stable revision implants. The purpose of this study is to compare the rates of repeat infection after 2-stage revision for prosthetic joint infection in patients who have retained cement or hardware compared to those who had complete removal.

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Home oxygen therapy (HOT) is prescribed to patients with pulmonary dysfunction to improve survival and quality of life. However, ignition of oxygen can lead to burns with significant morbidity and mortality. Providers who routinely treat this patient population face an ethical issue: balancing the obligation to provide beneficial treatment to a patient with the responsibility to protect that patient from suffering avoidable burn injuries.

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Fruit and vegetable wastes are linked to the depletion of natural resources and can pose serious health and environmental risks (e.g. eutrophication, water and soil pollution, and GHG emissions) if improperly managed.

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Article Synopsis
  • Ovarian carcinoma is often detected at advanced stages, leading to poor prognosis, highlighting the need for new biomarkers for patient outcomes.
  • The study utilized the 297-11A monoclonal antibody to analyze specific glycan structures in ovarian carcinoma and found a correlation between the presence of these sulfated glycans and patient prognosis.
  • The research identified that 297-11A-sulfated glycans are mainly expressed in serous and endometrioid carcinomas and are associated with shorter progression-free survival, suggesting their potential as a reliable prognostic marker.
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Frequent detection of sulfonamides (SAs) pharmaceuticals in wastewater has necessitated the discovery of suitable technology for their sustainable remediation. Adsorption has been widely investigated due to its effectiveness, simplicity, and availability of various adsorbent materials from natural and artificial sources. This review highlighted the potentials of carbon-based adsorbents derived from agricultural wastes such as lignocellulose, biochar, activated carbon, carbon nanotubes graphene materials as well as organic polymers such as chitosan, molecularly imprinted polymers, metal, and covalent frameworks for SAs removal from wastewater.

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The current study had conducted the life cycle analysis (LCA) to assess the environmental impact of microalgal wastewater treatment via an integrated membrane bioreactor. The functional unit selected for this analysis was 1 kg of treated microalgal wastewater with contaminants eliminated by ultrafiltration membrane fabricated from recycled polyethylene terephthalate waste. Meanwhile, the applied system boundary in this study was distinguished based on two scenarios, namely, cradle-to-gate encompassed wastewater treatment only and cradle-to-cradle which included the reutilization of treated wastewater to cultivate microalgae again.

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