Publications by authors named "Khondkar Siddique-E-Rabbani"

Accurate assessment of Respiratory Rate (RR) is the most important mechanism in detecting pneumonia in low-resource settings. Pneumonia is a disease with one of the highest mortality rates among young children under five. However, the diagnosis of pneumonia for infants remains challenging, especially in low- and middle-income countries (LMIC).

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Background: Based on published experimental evidence, a recent publication revealed an anomalous phenomenon in nerve conduction: for myelinated nerves the nerve conduction velocity (NCV) increases with stretch, which should have been the opposite according to existing concepts and theories since the diameter decreases on stretching. To resolve the anomaly, a new conduction mechanism for myelinated nerves was proposed based on physiological changes in the nodal region, introducing a new electrical resistance at the node. The earlier experimental measurements of NCV were performed on the ulnar nerve at different angles of flexion, focusing at the elbow region, but left some uncertainty for not reporting the lengths of nerve segments involved so that the magnitudes of stretch could not be estimated.

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Nasogastric feeding is commonly used to deliver enteral feed in critically ill patients and several methods are used for assessing the gastric residual volume with limitations. A new approach for gastric emptying time measurement has been developed using Electric Impedance Method (EIM). The study aims to establish whether EIM is useful for measuring gastric emptying during nasogastric feeding compared with nasogastric suction.

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Stretching in membranes of cells and vesicles plays important roles in various physiological and physicochemical phenomena. Irreversible electroporation (IRE) is the irreversible permeabilization of the membrane through the application of a series of electrical field pulses of micro- to millisecond duration. IRE induces lateral tension due to stretching in the membranes of giant unilamellar vesicles (GUVs).

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Article Synopsis
  • Tetrapolar impedance measurement (TPIM) with four electrodes helps reduce skin contact impedance, allowing for better electrical impedance analysis of biological tissues.
  • A new six-electrode TPIM configuration aims to enhance sensitivity in deeper tissue regions by adding additional potential electrodes on the opposite side of the cylindrical volume conductor.
  • Finite element simulations and experimental studies demonstrated that this new setup doubled sensitivity in the central region, making it beneficial for investigating deep organs like the lungs, stomach, and bladder.
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