[The effect of the extremely weak field on the cultures of bacteria Escherichia coli and Staphylococcus aureus].

The effect of extremely weak human electromagnetic field on the suspensions of Escherichia coli and Staphylococcus aureus in a physiological solution at 25 degrees C was studied. The results obtained indicate that the human field induces changes in the physical properties of liquid water in physiological solution and the induced structural and dynamic rearrangements of extracellular water are tranferred to bacterial cells and change their functional activity.

[Hormonal correction in combined therapy of temporomandibular joint dysfunction in women].

Pain dysfunction syndrome of the temporomandibular joint (TMJ) in women is often accompanied by mammary and reproductive disorders associated with endocrine disturbances. 30 female patients aged 19-35 years suffering from of the pain dysfunction syndrome TMJ combined with intact dentition and orthognathic occlusion were studied. Dental examination was followed by gynecologic examination.

[Steroidogenesis disorders in women with temporomandibular dysfunction].

The aim of the study was to trace hormone shifts in women suffering from different manifestation of the TMJ pain dysfunction syndrome. Levels of some blood steroid hormones (oestradiol, progesterone, testosterone, cortisol) were determined in 193 female patients aged 14-70. The object of study was blood serum collected in different menstrual phases.

[Photomodification of autologous blood in surgery].

The use of the method of autologous blood photomodification in surgery is discussed on basis of generalized experience of the Leningrad Research-Practical Center of Blood Photomodification (3,000 procedures conducted in over 2,000 patients). The current state of the problem, the main mechanisms of the therapeutic action of the procedure, and the clinical efficacy of the method in various surgical diseases are dealt with. The possible complications and the means of their prevention are deal with.

[Use of autoblood photomodification in combined therapy of patients with diabetes mellitus of the non-insulin-dependent type].

The paper is concerned with the results of a study of the effect of single reinfusion of photomodified autoblood on the level of plasma hormones, lipid peroxidation and antioxidant system of erythrocytes, the activity of the main enzymes of glucose metabolism in erythrocytes, the state of cellular immunity in 45 patients with non-insulin-dependent diabetes mellitus (NIDDM) in 1.7 and 14 days after autoblood photomodification (BPM). BPM was shown to cause a prolonged effect of the activation of intracellular glucose metabolism, a decrease in the endogenous insulin consumption by tissues, and a decrease in the blood concentration of hormones of contrainsular action.

[Spectral characteristics of the mechanism of oxidase activity of ceruloplasmin].

The absorbance and EPR spectra of type 1 and 2 copper-binding centres which are present in ceruloplasmin (Cp) molecule were shown to disappear upon the reduction of the enzyme by ascorbate under anaerobic conditions. The fluorescence band attributed to type 3 Cu was altered concomitantly. The electron-accepting nitroxyl radical added to reduced Cp restored the absorbance, EPR and fluorescence spectra of the oxidase.

[The use of preserved photomodified autoblood for the prevention of thromboembolic complications in surgical interventions on the small pelvis].

The method of UV irradiation of autoblood followed by infusion in the early postoperative period was used in 109 patients subjected to various operative interventions on the small pelvis organs. It was established that the infusion of autologous photomodified blood allowed to avoid postoperative thromboembolic complications.

[Photomodification of human immunocompetent blood cells].

Near-UV irradiation (280-365 nm) at non-lethal doses increased lymphocyte E and EAC rosette-forming capacity, reduced cell proliferation in response to mitogen (PHA), induced an increase in the content of lipid peroxidation products in the cell culture medium. An antioxidant (alpha-tocopherol, 10(-7) M) administered before or immediately after near UV irradiation of lymphocytes reduced the above effects. The addition of an antioxidant to the culture medium 90 min after cell irradiation failed to reduce lymphocyte rosette-forming capacity.

[Mechanism of biological action of UV-irradiated blood].

It has been found that under UV-irradiation of the blood serum at 77 K free radicals are formed as a result of photodestruction of protein molecules. The protein molecule fragments play a role of antigens which during the transfusion of blood (blood serum) initiate immune reactions bringing about polyimmunization of human organism.