Cytokine Gene Expression Alterations in Human Macrophages Infected by .

Objective: Leishmaniasis is caused by members of the species and constitute a group of infective diseases that range from cutaneous lesions to lethal visceral forms. In infected persons, macrophages recognize and eliminate the parasites via phagocytosis. In order to change a hostile environment into an environment adequate for survival and reproduction, the engulfed Leishmania species needs to modulate the function of its host macrophage.

Population-based Seroprevalence of HTLV-I Infection in Golestan Province, South East of Caspian Sea, Iran.

Objective(s): Human T-cell lymphotropic virus type-1 is an oncornavirus that causes adult T cell leukemia (ATL) HTLV-I-associated myelopathy⁄tropical spastic paraparesis (HAM/TSP). Golestan province is located in North West of Khorasan province known as an endemic area for HTLV-I in Iran. This study aimed to evaluate seroprevalence of HTLV-I in Golestan province.

Lymphomas in Golestan province of Iran: results of a population-based cancer registry.

Introduction: Malignancies of lymphoid cells can be divided into Hodgkin and non-Hodgkin lymphomas (NHL) on the basis of pathologic features, clinical manifestations and treatment. In this paper we present data on lymphomas in Golestan province, in the northeast of Iran, during 2004-2006, using three years results of the Golestan population-based cancer registry (GPCR), a voting member of the International Association of Cancer Registries (IACR).

Methods: GPCR started collecting data on all cancers from all public and private diagnostic and therapeutic centers (hospitals, specialist physicians' offices, pathology, laboratory, and imaging centers) of Golestan province in 2004.

Prevalence of hepatitis D virus infection in hepatitis B surface antigen-positive subjects in Golestan province, northeast Iran.

Background And Purpose: Hepatitis D virus (HDV) is a defective RNA virus dependent on hepatitis B virus (HBV) infection for its replication and expression. It is known that coexistent infection with HDV tends to aggravate the course of HBV-associated liver disease. This study was carried out to determine the seroprevalence of HDV among hepatitis B surface antigen (HBsAg)-positive individuals in the northeast part of Iran.

Prevalence of hepatitis D virus infection in HBsAg positive subjects in Iran.

This study was carried out to determine the seroprevalence of hepatitis D virus among HBsAg positive individuals in the northeast part of Iran. One hundred thirty nine HBsAg positive subjects detected from a population based single stage cluster sampling in Golestan province of Iran were enrolled. All cases were evaluated for the presence of anti-HDV antibodies using commercially available ELISA kits.

Seroprevalence of hepatitis B virus and its co-infection with hepatitis D virus and hepatitis C virus in Iranian adult population.

Context: Hepatitis B virus (HBV) infection is one of the most prevalent public health problems worldwide (especially in developing countries).

Aims: This study was carried out to determine the seroprevalence of HBV and its co-infection with hepatitis D (HDV) and C (HCV) viruses in the northeastern part of Iran.

Setting And Design: A population-based cross-sectional study in Iran.

Hepatitis B/C virus co-infection in Iran: a seroepidemiological study.

Background/aims: As hepatitis B and C virus have the same transmission routes, dual infection may occur. The aim of this study was to determine the seroprevalence of HCV in HBsAg-positive subjects.

Methods: 139 HBsAg-positive subjects were enrolled in the study.

Effects of Ramadan fasting on serum low-density and high-density lipoprotein-cholesterol concentrations.

Background: The aim of the study was to determine the status of low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C) in human subjects during Ramadan fasting. Fasting during Ramadan (one month of food and water intake restricted only to night hours) is a religious obligation for Muslims. There are biochemical effects of changes in lifestyle during Ramadan.

Crimean-Congo hemorrhagic fever: case series from a medical center in Golestan province, Northeast of Iran (2004).

Crimean-Congo hemorrhagic fever (CCHF) is a widely distributed lethal disease, worldwide. Humans are usually infected with CCHF virus through a tick bite or close contact with viral contaminated tissues or with blood of domestic animals or of infected patients. The present study reports six cases of CCHF, who were in contact with both infected tissues and blood from sheep.

Relationship between malondialdehyde level and glutathione peroxidase activity in diabetic rats.

Background: This investigation describes the relationship between glutathione peroxidase activities, an antioxidant enzyme, and the oxidative status in diabetic rat blood.

Methods: Malondialdehyde level and glutathione peroxidase activity were measured by spectrophotometric techniques.

Results And Conclusions: Malondialdehyde content in the diabetic rats group was increased compared to that in the controls [3.