Urinary detection in prostate cancer by magnetic nanoparticles coupled with colorimetric enzyme-linked oligonucleotide assay.

is one of the most prostate cancer-specific genes described to date. Of note, expression is detectable at high level in the urine of prostate cancer (PCa) patients. Accordingly, is an ideal biomarker for PCa diagnosis.

Colorimetric detection of PCA3 in urine for prostate cancer diagnosis using thiol-labeled PCR primer and unmodified gold nanoparticles.

Background: PCA3, a non-coding RNA, has been approved as a potential urinary biomarker for prostate cancer. However, PCA3 urine tests have some limitations. Therefore, we developed a colorimetric method for PCA3 detection in urine.