siRNA-based therapy for overcoming drug resistance in human solid tumours; molecular and immunological approaches.

RNA interference (RNAi) is a primordial biological process that protects against external intrusion. SiRNA has the potential to selectively silence disease-related genes in a sequence-specific way, thus offering a promising therapeutic approach. The efficacy of siRNA-based therapies in cancer treatment has gained significant recognition due to multiple studies demonstrating its ability to effectively suppress cancer cells' growth and multiplication.

Evaluation of IL-6 and IL-17A gene polymorphisms in Iraqi patients infected with COVID-19 and type 2 diabetes mellitus.

Background: In patients with COVID-19, diabetes mellitus type 2 (T2DM) increases the risk of hospitalization and death. Patients who have IL-6 and IL-17A single nucleotide polymorphisms (SNPs) are more likely to have severe COVID-19. This study aims to determine whether SNPs of the IL-6 gene at rs1800795 (G > C) and the IL-17A gene at rs2275913 (G > A) are associated with COVID-19 and T2DM in the Iraqi population.

The role of Serum Interleukin-4 and Interleukin-6 in Helicobacter pylori-infected patients.

Background: Helicobacter pylori (H. pylori) is a Gram-negative bacteria that colonizes the gastrointestinal mucosa and causes chronic inflammation.

Aims: There are several studies related to cytokines concentrations in H.

p53, p21, and cyclin d1 protein expression patterns in patients with breast cancer.

Background And Aim: The mutation in the wild-type tumor suppressor gene p53 is the most common genetic change in human tumors. In addition, the normal function of p21, which is both antiproliferative and an inhibitor of the cell cycle, is disrupted in some types of cancer. Meanwhile, cyclin D1 is a member of the cyclin protein family that is involved in regulating cell cycle progression.

Molecular Detection of Gene in serovar Typhi Isolated from Typhoid Patients in Baghdad.

Background And Objective: Typhoid fever is endemic in most countries, causing major public health problems with high morbidity and mortality, the resistance of Salmonella enterica serovar Typhi (S. Typhi) towards antimicrobials is recently increased. The aim was to detect the harboring gyrA gene in Typhi Salmonella enterica serovar.

Distribution of Pantoea agglomerans isolates and molecular detection of bla ESβL gene: A statistical study.

The Purpose: to study the distribution of Pantoea agglomerans (P. agglomerans) statistically and the presence of bla type ESβL in the clinical and environmental isolates.

Methods: During a period of 2014-2015, 895 blood specimens and 438 hospital environmental samples were collected from one children's hospital in Baghdad city.