NEURAL TUBE DEFECTS AND MICRONUTRIENTS DEFICIENCY PREVALENCE IN GEORGIA.

Until 2015, systematic statistical data on micronutrient deficiency was not available in Georgia, to provide developing national strategy. In the same year, the National Centre for Disease Control and Public Health of Georgia (NCDC) in collaboration with the USA CDC launched the project "Strengthening surveillance of micronutrient deficiency in Georgia". In 2015 we did choose sentinel surveillance approach.

ATTENTION DEFICIT HYPERACTIVITY DISORDER AND HAIR HEAVY METAL AND ESSENTIAL TRACE ELEMENT CONCENTRATIONS. IS THERE A LINK?

The aim of our study was to assess hair micro-elemental status in children with attention deficit hyperactivity disorder, determine micro-elemental misbalances and heavy metal concentrations and evaluate its impact on child behavior. Case-control study was conducted at Child Development Center of M. Iashvili Children's Central Hospital in 2015-2017years (Tbilisi, Georgia).

EVALUATION OF DEVELOPMENTAL OUTCOMES WITH BAYLEY III TEST IN PRETERM INFANTS WITH RESPIRATORY DISTRESS SYNDROME.

Aim of our study was assessment of developmental outcome of neonates with respiratory distress syndrome, evaluation of the impact of RDS on child's health, growth and neurodevelopment at 2 years of age. Case control study included 138 children, from those, 74 preterm (gestational age 32-36 weeks), who were divided into 2 study groups: I groups - involved 38 preterm with RDS and II group - 36 preterm patients without RDS and other neonatal problems. Control group included 42 patients born term with uncomplicated history.

HAIR HEAVY METAL AND ESSENTIAL TRACE ELEMENT CONCENTRATION IN CHILDREN WITH AUTISM SPECTRUM DISORDER.

Our study aims evaluation of level of essential trace elements and heavy metals in the hair samples of children with autistic spectrum disorder (ASD) and identification of changes that are associated with autistic spectrum disorders. Case-control study was conducted at Child Development Center of Iashvili Children's Central Hospital (LD).We studied 60 children aged from 4 to 5 years old.

ASSOCIATION BETWEEN SHORT STATURE AND HAIR ELEMENTS.

Aim - assessment of hair elemental status, determination of elemental imbalances and heavy metal concentration and evaluation its impact on child liner growth. Case-control study involves 112 children less than 5 years old (target group - 54 children with short stature, control - 58 children with normal physical development). Medical history, nutritional status, anthropological parameters were assessed.

INCIDENCE OF ALLERGIC RHINITIS AND RESPIRATORY INFECTIONS IN FIRST GRADE SCHOOL CHILDREN IN GEORGIA.

The aim of the study was assessment of incidence of allergic rhinitis and respiratory infections and evaluation of quality of life of first grade school age children with allergic rhinitis. The cross sectional study in randomly selected regions and schools was conducted using specially developed parent questionnaire and mini rhino conjunctivitis quality of life questionnaire (MiniRQLQ). On the first was used special questionnaire, and on the second phase MiniRQLQ was used in cases with allergic rhinitis.

PREVALENCE OF ATOPIC DERMATITIS SYMPTOMS IN CHILDREN WITH DEVELOPMENTAL AND BEHAVIORAL PROBLEMS.

A link between atopic dermatitis (AD,eczema) and emotional and behavioral dysfunction is more or less well recognized but concern still exists. Children with a chronic health condition have long been considered at excess risk for psychosocial morbidity. But psychosocial morbidity is less linked and studied in connection with other disease, especially AD.

Cost-effectiveness of pneumococcal conjugate vaccination in Georgia.

Objective: Financial support from the Global Alliance for Vaccines and Immunization (GAVI) to introduce the 10-valent pneumococcal conjugate vaccine (PCV10) into the routine childhood immunization schedule in Georgia is ending in 2015. As a result, the Interagency Coordination Committee (ICC) decided to carry out a cost-effectiveness analysis to gather additional evidence to advocate for an appropriate evidence-based decision after GAVI support is over. The study also aimed to strengthen national capacity to conduct cost-effectiveness studies, and to introduce economic evaluations into Georgia's decision-making process.

Infants' complementary feeding and factors influencing its timing.

The aim of our study was to detect factors that influence timing and adequacy of complementary feeding (CF) practices in Georgian families. The study was conducted at M. Iashvili Central Children's Hospital Child Developmental Center in 2013-2014 year.

Evaluation of nutritional knowledge of second grade school children and assessment of their dietary intake.

The aim of the study was assessment of the general nutrition knowledge and physical activity rate among the first grade school age children and evaluation of their diet and nutritional skills based on the parental interviews. Cross-sectional study was conducted in randomly selected schools of Tbilisi. In each school was selected one group of the second grade children and their parents by cluster selection method.

Correspondence of treatment of acute diarrhea to who recommendations in georgia.

The aim of this study was to analyze Georgian health care practitioners' knowledge on management of acute diarrhea and its adherence to WHO treatment guidelines. A questionnaire-based, cross-sectional survey was carried out in hospitals and out-patient clinics of Georgia. 350 anonymously filled questionnaires were analyzed (27% - hospitals, 73% - out-patient clinics).

The parameters of physical growth in 5-6 years old children in Tbilisi.

The aim of the study was to assess nutritional status and anthropometric parameters in children aged 5-6 and to identify possible factors influencing the growth pattern of Georgian children. The cross-sectional study was performed on a sample of 754 children boys and girls aged 5-6 attending preschool facilities and their main caregivers in the study sites. The study covered children population from 16 kindergartens of 2 regions (Gldani-Nadzaladevi, and Vake-Saburtalo) of Tbilisi, with different social-economical status.

[Peculiarities of joint course of allergic rhinitis and bronchial asthma in population of school-age children].

Purpose of the work was to investigate clinical-allergic peculiarities of allergic rhinitis, together with bronchial asthma in school-age children. There were studied random representative group of children, in total 3000 subjects from 6 to 17. According to the results of epidemiological research in school-age children's population, prevalence of allergic rhinitis was 13,2%.

Non-viral wheezing in preschool children: the effect of inhaled fluticasone on symptoms and lung function.

Aims of this study were: to evaluate changes in lung function in wheezing children with detected MP and CP infection according to treatment; to measure the response to inhaled corticosteroids in children with significant wheezing who were selected as having a high risk of progressing into childhood asthma. 54 children were randomly assigned 2:1 into 2 groups-the main group (36 patients), in which inhaled corticosteroids were administered, and the control group (18 patients), without inhaled corticosteroids. Serum IgE levels were determined using the ELISA (reagents: IBL-Hamburg).

[INF-gamma during respiratory-syncytial induced obstructive respiratory syndrome in infection in children under one year of age].

Lately the connection of Asthma and RSV drew the sufficient attention. The recurrent wheezing developed during the RSV in children is particularly frequent in the families having history of atopy. The decreased expression of INFgamma may play the role in the pathogenesis of RSV infection.