Association of M470V polymorphism of CFTR gene with variability of clinical expression of asthma: Case-report study.

Introduction And Objectives: Asthma is a complex genetic disorder. Several genes have been found associated with asthma. The cystic fibrosis transmembrane conductance regulator (CFTR) gene is one of them.

[First seizure in children. Exploration strategy].

We have carried out a retrospective study on 51 children aged between 2 years 3 months and 13 years in order to determine the findings and to define the indications of neuroimaging modalities in children with a first unprovoked seizure. Children who had neuroimaging studies were divided into two groups based on the results of neuroimaging normal or abnormal. We have compared the two groups according to each clinical and electroencephalographic parameters studied.