[Analysis of intracranial saccular aneurysm wall: neuroimaging and histopathological correlates].

Background: Contrast enhancement of intracranial aneurysm wall during MRI with targeted visualization of vascular wall correlates with previous aneurysm rupture and, according to some data, may be a predictor of further rupture of unruptured aneurysms.

Objective: To analyze possible causes of aneurysm contrast enhancement considering morphological data of aneurysm walls.

Material And Methods: The study included 44 patients with intracranial aneurysms who underwent preoperative MRI between November 2020 and September 2022.

[Pathological tortuosity of intracranial arteries (pure arterial malformation) - diagnosis and management tactics].

Background: Tortuosity of intracranial arteries is rare and usually mistaken for arteriovenous malformations. In the world literature, the term «pure arterial malformations» is used to refer to this disease.

Objective: To summarize the experience of the Burdenko Neurosurgery Center on diagnosis of intracranial artery tortuosity, management and treatment of these patients, as well as to review appropriate literature data.

Magnetic resonance imaging of saccular intracranial aneurysm wall.

Background: Hemorrhage from intracranial aneurysms is associated with high risk of adverse outcomes. In this regard, surgical treatment of unruptured asymptomatic aneurysms has been actively developed in recent decades. One of the objectives is searching for predictors of aneurysm rupture to clarify the indications for surgery.

Giant Middle Cerebral Artery Aneurysms: A 55-Patient Series.

Background: The treatment of middle cerebral artery (MCA) giant aneurysms (GAs) represents a challenging task.

Methods: The data for 55 patients treated for MCA GA (≥25 mm) at the N.N.

[Surgical treatment of patients with cerebral aneurysms in the acute stage of rupture: dynamics of results during 2006-2018].

Unlabelled: Treatment of cerebral aneurysms in the acute stage of subarachnoid hemorrhage (SRH) especially on the background of cerebral vasospasm continues to be a difficult task.

Objective: Assessment of dynamics of the surgical treatment results of patients with cerebral aneurysms in acute period of SRH.

Material And Methods: A comparative analysis of the results of patients' surgical treatment in NMRCN Burdenko about aneurysm in 1-21 days after hemorrhage was made.

[Intra-arterial administration of verapamil for prevention and treatment of cerebral angiospasm after SAH due to cerebral aneurysm rupture].

Aim: The study purpose was to analyze the efficacy of intra-arterial administration of verapamil (IAV) in the treatment of angiospasm in SAH patients and to determine optimal parameters of the procedure. A number of studies demonstrated the efficacy of intra-arterial administration of vasodilators, in particular verapamil, in the treatment of angiospasm after aneurysmal SAH, which served the basis for inclusion of this method in the recommended protocol for treatment of SAH patients [1-7].

Material And Methods: We analyzed the efficacy of IAV in 35 patients in the acute period of SAH, with 77.

Treatment of Brain Arteriovenous Malformations with Hemodynamic Aneurysms: A Series of 131 Consecutive Cases.

Background: The natural history of hemodynamic aneurysms (HAs) associated with brain arteriovenous malformations (AVMs) remains controversial, with no single approach to treatment. The purpose of this study was to justify preventive treatment tactics for HAs that pose an increased risk of rupture based on hemodynamic studies demonstrating hypertension in the afferent bed after AVM exclusion.

Methods: This retrospective analysis included 131 of 1740 patients (8%) with brain AVMs and at least 1 aneurysm treated at Burdenko Neurosurgical Institute between 2000 and 2016.

[Surgical treatment of a pregnant female with AVM hemorrhage].

Hemorrhages from arteriovenous malformations (AVMs) in pregnant females are rare, but they are known to lead to high maternal and infant mortality. There are no standards for AVM treatment in pregnant females. Many authors believe that AVM resection before delivery improves the prognosis for life and health of the mother and fetus.

De novo cerebral aneurysms.

Objective: To substantiate the reasonability and duration of angiographic follow-up of patients operated on for cerebral aneurysms to rule out de novo aneurysm formation.

Material And Methods: The results of angiographic examination (cerebral angiography and SCT angiography) of 43 patients with cerebral aneurysms operated on at the Burdenko Neurosurgical Institute in 1995-2012 are analyzed. The follow-up duration varied from 1 to 14 years after surgery (mean duration, 5 years).

Intraoperative indocyanine green fluorescence angiography in surgery of brain aneurysms. The first experience with using the technique and literature review.

Intraoperative blood flow assessment after aneurysm clipping has become a standard procedure in vascular neurosurgery worldwide. Intraoperative indacyanine green angiography (ICG) has recently been certified in Russia. Fifteen patients with aneurysms operated with ICG control in Burdenko NSI are described in present publication.

Long-term results of treatment of patients with large or giant intracranial aneurysms of internal carotid artery.

At Burdenko Neurosurgical Institute annually arrives 50-60 patients with large and giant aneurysms of the brain, which is nearly 15% of all patients with aneurysms. About half of them--patients with paraclinoid aneurysms, which are successfully treated by cliping using techniques of intravascular blood aspiration (IVBA) or proximal control of blood flow in the neck. This paper analyzes the long-term outcomes of patients who were operated for large and giant aneurysms of the internal carotid artery in the last 15 years.

[Local fibrinolysis in treatment of non-traumatic intracerebral hematomas and ventricular hemorrhages].

Local fibrinolysis and aspiration in treatment of spontaneous intracerebral hematomas (SIH) and ventricular hemorrhages (VH) have become a wide spread technique in dedicated cerebrovascular centers. Forty four patients treated in Burdenko NSI in 2007-2011 were evaluated. Local fibrinolysis for SIH were perfomed in 30 pt.

[Complex intracranial vascular pathology: multiple aneurysms combined with ICA aplasia].

Rare case of multiple aneurysms of posterior circulation associated with right ICA aplasia in 39 year old female patient is described. Detailed description of ICA aplasia is enclosed. Modern diagnostic methods (MRI-SWI) were performed to identify the bleeding source.

[Stepwise treatment of multiple cerebral aneurysms utilizing surgical and endovascular techniques].

To evaluate results of combined treatment of multiple intracranial aneurysms utilizing microsurgical clipping with endovascular techniques. Study group comprised 60 patients with 230 multiple aneurysms (MA) of different location. Most common were aneurysms of ICA--49% and MCA--24%.

[Diagnosis of the source of bleeding in multiple cerebral aneurysms by susceptibility-weighted imaging].

Objective: to evaluate the efficiency of susceptibility-weighted imaging (SWI) in diagnosing the source of bleeding in multiple cerebral aneurysms.

Subjects And Methods: This investigation enrolled 30 patients with multiple aneurysms (MA) treated at the N. N.

[Substantiation of differentiated management of patients with multiple cerebral aneurysms].

The study was performed to substantiate optimal tactics of management of patients with multiple cerebral aneurysms based on analysis of surgical results. This study included 233 (20%) patients with multiple cerebral aneurysms who were treated in Burdenko Neurosurgical Institute since 1995 till 2007. We analyzed results of single-stage (microsurgical technique) and multistage (microsurgical technique and step-by-step application of endovascular and microsurgical techniques) approaches.

[Microsurgical treatment of cerebral arteriovenous malformations in Burdenko Neurosurgical Institute (recent experience)].

Recently the number of AVM resections in Burdenko Neurosurgical Institute has been increased dramatically. Aim of this study was to assess the results of open surgery in our clinic in modern neurosurgical era. Consecutive series if 160 patients with AVM treated using microsurgical technique since 2009 till 2011 was analyzed.

[The role of susceptibility-weighted MRI in detection of ruptured aneurysm in multiple aneurysms].

Since 2008 till 2010 years 22 patients with multiple aneurysms were examined in Burdenko Neurosurgical Institute (Moscow, Russia). The series included 13 female and 9 male patients, age ranged from 28 to 62 years (mean 45 years). 68 aneurysms of different localization were discovered in these 22 patients.

Results of microsurgical treatment of large and giant ICA aneurysms using the retrograde suction decompression (RSD) technique: series of 92 patients.

Background: Microsurgical treatment of large and giant paraclinoid internal carotid artery (ICA) aneurysms often requires the use of the retrograde suction decompression (RSD) technique to facilitate clipping. Surgical results, functional outcomes at discharge, and technique limitations based on single institution series are presented.

Materials And Methods: Between 1996 and 2009, eighty-three consecutive patients (19 to 68 years, mean 45.

[Acute injuries to the upper gastrointestinal tract in patients with multiple cerebral arterial aneurysms].

The paper describes a case of multiple cerebral arterial aneurysms in a patient with prior subarachnoidal hemorrhage, who developed postoperative acute upper gastrointestinal tract (GIT) lesion manifesting itself as bleeding and requiring multiple endoscopic treatment procedures and eventually a direct surgical intervention. The susceptibility of patients with cerebral pathology to upper GIT lesions and methods of their therapy and prevention are discussed.

[Giant fusiform partially thrombosed aneurysm of fenestrated middle cerebral artery].

The authors describe a rare case of 15-year old patient with ruptured giant fusiform partially thrombosed aneurysm of fenestrated middle cerebral artery (MCA). The patient underwent surgical treatment: clipping of proximal and distal necks of aneurysm and thrombectomy. Intraoperative signs of MCA fenestration are described in details.

[Aneurysms of cerebral arteries in children and adolescents].

Background: Intracranial aneurysms are rare lesions in children and adolescents and their epidemiology, clinical and anatomic features are poorly understood. Aim of the study was to reveal the specific features of cerebral aneurysms in children and adolescents and to develop guidelines for management of these patients.

Materials And Methods: The study was performed on consecutive series of 125 patients under 18 years of age harboring 145 aneurysms.

[Neuropsychological signs in patients with arteriovenous malformations, cavernomas and hematomas of cerebellum].

Neuropsychological assessment was performed in 13 patients with arteriovenous malformations and 12 with cavernomas and hematomas of cerebellum before and after surgery. In all patients we identified syndromes that were similar to the damage of different areas of neocortex (predominately frontal lobe). Apraxia and disturbance of verbal memory were the most frequent signs.

[Microsurgical treatment of large and giant aneurysms of the internal carotid artery: analysis of application of intravascular blood aspiration technique and future perspectives].

The article discusses results of surgical treatment of 82 patients with large and giant cerebral aneurysms operated in Burdenko Neurosurgical Institute (Moscow, Russia) during the recent 14 years. Special attention was given to benefits of intravascular blood aspiration (IBA) technique. This technique was proven to be very effective, allowing to clip the aneurysm in 87.

[Cognitive disturbances in patients with arteriovenous malformations, cerebellar cavernomas and hematomas].

A clinical-neuropsychological study using Luria's method has been conducted in 13 patients with arteriovenous malformations (AVM) and 12 patients with cerebellar cavernomas and hematomas. The syndromes were similar to lesions of the large hemisphere cortex, more often of premoter regions and less often of the cortex of posterior hemispheric regions. After a surgery on the right cerebellar hemisphere, some patients had perseverations and micrographia in writing.