Publications by authors named "Khayri Azizi Kamel"

Article Synopsis
  • - CHIKV cases in Malaysia increased from 2019 to 2021, likely due to the virus spreading from neighboring countries and a genotype shift from earlier outbreaks, particularly linked to the Indian Ocean Islands outbreak in 2004.
  • - An analysis of 56 CHIKV positive serum samples from Tangkak, Johor highlighted that the 2021 outbreak strains bore an ECSA-IOL genotype, closely resembling strains from a 2018-2019 outbreak in Thailand and showing mutation adaptations favoring different mosquito vectors.
  • - The findings suggest the 2021 outbreak in Malaysia is connected to strains from the Indian subcontinent via Thailand, with notable genetic mutations potentially enhancing the virus's ability to spread and adapt to
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Recently, wastewater-based epidemiology (WBE) research has experienced a strong impetus during the Coronavirus disease 2019 (COVID-19) pandemic. However, a few technical issues related to surveillance strategies, such as standardized procedures ranging from sampling to testing protocols, need to be resolved in preparation for future infectious disease outbreaks. This review highlights the study characteristics, potential use of WBE and overview of methods, as well as methods utilized to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) including its variant in wastewater.

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Objectives: This study reported SARS-CoV-2 whole genome sequencing results from June 2021 to January 2022 from seven genome sequencing centers in Malaysia as part of the national surveillance program.

Methods: COVID-19 samples that tested positive by reverse transcription polymerase chain reaction and with cycle threshold values <30 were obtained throughout Malaysia. Sequencing of SARS-CoV-2 complete genomes was performed using Illumina, Oxford Nanopore, or Ion Torrent platforms.

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