Design and evaluation of screening and self-care (mobile) application for oral and dental problems and emergencies.

Introdution: Although oral and dental diseases may occur in unexpected or even emergency conditions, but some of the diagnosis and treatments can be algorithmically done following some guidelines. The development and implementation of a system that provides users with a record of history and a proposal of required actions can be not only efficiently practical, but also virtually simple.

Materials And Method: A system made up of web and mobile apps is proposed and evaluated for screening and self-care of oral and dental problems and for providing advice on dental emergencies and therapeutic measures.

Application of machine learning in breast cancer survival prediction using a multimethod approach.

Breast cancer is one of the most prevalent cancers with an increasing trend in both incidence and mortality rates in Iran. Survival analysis is a pivotal measure in setting appropriate care plans.  To the best of our knowledge, this study is pioneering in Iran, introducing a multi-method approach using a Deep Neural Network (DNN) and 11 conventional machine learning (ML) methods to predict the 5 year survival of women with breast cancer.

Epidemiology of malignant gliomas in Iran: first report of Iranian National Population-based Cancer Registry, 2009-2017.

Objective: Malignant gliomas constitute the most common type of primary malignant brain tumors. Most previous studies have evaluated the epidemiology of malignant gliomas in developed countries. Hence, there is a lack of evidence in this regard from developing countries.

Comparison performance of the Bayesian Approach with the Weibull and Birnbaum-Saunders distributions in imputation of time-to-event censors.

Almost all survival data is censored, and censor imputation is necessary. This study aimed to investigate the performance of the Bayesian Approach (BA) in the imputation of censored records in simulated and Breast Cancer (BC) data. Due to the difference in the distribution of time to event in survival analysis, two well-known the Weibull and Birnbaum-Saunders (BS) distributions have been used to test the performance of the BA.

Survival analysis of recurrent breast cancer patients using mix Bayesian network.

Introduction: Breast cancer (BC) is the most common cancer among women. Iranians have an 11% BC recurrence rate, which lowers their survival rates. Few studies have investigated cancer recurrence survival rates.

Epidemiology and survival of cervical cancer in Iran based on national cancer registry data (2008-2014).

Background: Cervical cancer (CC) is the third most commonly diagnosed cancer and the fourth leading cause of cancer death in females worldwide, associated with the incidence of human papillomavirus (HPV) infection. The CC incidence is low in Iran, ranking 11th among cancers. This study aimed to estimate the survival rate of CC and the reasons for its low survival rate based on the data retrieved from the Iranian National Cancer Registry System.

Exosomal circular RNAs: New player in breast cancer progression and therapeutic targets.

Breast cancer is the most prevalent type of malignancy among women. Exosomes are extracellular vesicles of cell membrane origin that are released exocytosis. Their cargo contains lipids, proteins, DNA, and different forms of RNA, including circular RNAs.

Ten-Year Survival of Breast Cancer in Iran: A National Study (Retrospective Cohort Study).

Purpose: This study aimed to estimate the 5- and 10-year survival rates of breast cancer in Iran.

Methods: This retrospective cohort study was performed in 2019 on breast cancer patients registered in the national cancer registry system of Iran during 2007-2014. The patients were contacted to collect their information and status (alive or dead).

Are HOMA-IR and HOMA-B good predictors for diabetes and pre-diabetes subtypes?

Background: To investigate the association between the Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) and Homeostasis Model Assessment of Beta-cell function (HOMA-B) with the incidence of diabetes and pre-diabetes subtypes.

Methods: A total of 3101 normoglycemic people aged 20-70 years were included in the 6-year follow-up study. Multinomial logistic regression was used to calculate the incidence possibility of isolated Impaired Fasting Glucose (iIFG), isolated Impaired Glucose Tolerance (iIGT), Combined impaired fasting glucose & impaired glucose tolerance (CGI), and Diabetes Mellitus (DM) per standard deviation (SD) increment in HOMA-IR and HOMA-B in the crude and multivariable model.

The Effect of Neoadjuvant vs Adjuvant Chemotherapy on Final Outcome of Patients with Triple Negative Breast Cancer.

Triple negative breast cancer (TNBC) accounts for about 10% to 20% of breast cancers, does not respond to endocrine treatment, and is more aggressive. Two chemotherapy methods suggested include neoadjuvant chemotherapy (NAC), performed before surgery, and adjuvant chemotherapy (AC), performed after surgery. In order to determine whether the choice of chemotherapy method has any impact on patients' outcome, the present study aimed to compare the overall survival (OS) and disease-free survival (DFS) of TNBC patients with a 10-year follow-up.

Emerging role of extracellular vesicles in the pathogenesis of glioblastoma.

While brain tumors are not extremely frequent, they cause high mortality due to lack of appropriate treatment and late detection. Glioblastoma is the most frequent type of primary brain tumor. This malignant tumor has a highly aggressive behavior.

Dental practice in the era of COVID-19: A review of literature.

Dental practitioners confront the highest risk of COVID-19 infection due to constant exposure to saliva, droplets, blood, and aerosols. Despite the suspension of routine dental care in many countries around the world, dental professionals perceive a moral duty to take part in the global fight against the pandemic. Therefore, dental professionals should be vigilant in defending against the transmission of the virus and as well as in the diagnosis of the disease through the oral manifestations of it.

Five-Year Survival Rate of Bladder Cancer in Iran during 2001-2007.

Background & Objective: Bladder cancer is the fourth most common cancer in men and the most common cancer in women, comprising 8% of all males and 3% of female tumors. The present study aimed to estimate the five-year survival rates of bladder cancer in Iran.

Methods: Information on 3,337 registered cases of bladder cancer was obtained from the Office of National Cancer Registry in the Ministry of Health and Medical Education (MOH & ME).

Relationship between Parafunctional Habits and Salivary Biomarkers.

Objectives: Parafunctional habits, as one of the etiological factors of temporomandibular disorders (TMD), are an individual's response to increased stress. During stress and depression, biomarkers such as cortisol and salivary alpha-amylase (SAA) are secreted in the saliva. The present study aimed to investigate whether there is a correlation between salivary stress biomarkers and parafunctional habits.

Survival Rate and Prognostic Factors among Iranian Breast Cancer Patients.

Background: Survival time is one of the indicators used for evaluation of the quality of care in different types of malignancies, including breast cancer. The present study aimed to estimate the survival rate of breast cancer and its related factors among Iranian patients.

Methods: Overall, 3148 cases of breast cancer who referred to the Cancer Research Center in Shahid Beheshti University of Medical Sciences, Tehran, Iran during 1994-2017 participated in this longitudinal study.

Applying dental implant therapy in patients with oral lichen planus: a review of literature.

Lichen planus (LP) is a violent, paranormal inflammatory disease that can affect the skin or any lining of the mucous membrane. LPs are a branch of immune-mediated inflammatory disease (IMID) that collaborates with the function and structure of the immune system that are precipitated through various etiological infectious agents. Oral lichen planus (OLP) is one of the most common kinds of IMID.

Saving the Breast Saves the Lives of Breast Cancer Patients.

Unlabelled: . Surgery has been known as the procedure of choice for breast cancer management since 1700 years before Christ. Nowadays, breast-conserving surgery and mastectomy are performed in selected cases with specific clinical criteria.

Using Nanochelating Technology for Biofortification and Yield Increase in Rice.

Iron is a vital microelement that plays an important role in plant metabolism. Consuming a large amount of chemical fertilizers increases the risk factors of neoplastic diseases such as heavy metals and harmful components in crops edible parts. Therefore, utilizing novel technologies to increase yields without requiring more chemical fertilizers seems essential.

Efficacy of Low-Level Laser, Hard Occlusal Appliance and Conventional Pharmacotherapy in the Management of Myofascial Pain Dysfunction Syndrome; A Preliminary Study.

Myofascial pain dysfunction syndrome (MPDS) is a common temporomandibular joint disorder. Due to its multifactorial etiology, treatment usually involves more than one modality to obtain complementary results. The purpose of this study was to compare the combined effect of a low-level laser, a hard occlusal appliance, and conventional pharmacotherapy with pharmacotherapy only in the management of patients with MPDS.

The Relationship of Pre and Early Postnatal Risk Factors with Breast Cancer.

Background: Breast cancer (BC) is the most prevalent cancer in Iranian women and the fifth most common cause of cancer-related death in Iran. Risk factors in the adult life may act during fetus life and after delivery. We conducted a case-control study to find out the relation of in utero and early life exposure and risk of BC.

Determining salivary and serum levels of iron, zinc and vitamin B in patients with geographic tongue.

Benign migratory glossitis or geographic tongue, whose cause still remains a mystery, emerges as annular lesions on the dorsal surface of the tongue. Several reasons have been reported for this condition, including vitamin deficiencies, digestive disorders, emotional stress and nutritional deficiencies. In order to introduce an efficient treatment for the geographic tongue, the present study investigated the levels of iron, zinc and vitamin B in the blood and saliva.

The effect of low level laser on number of Candida albicans colonies in-vitro: a new finding.

Background: Candida albicans is a commensal organism that causes a wide variety of diseases in humans. One of these diseases is oral candidiasis, which occurs at a high recurrence rate in spite of available treatments. The purpose of this study was to compare the effect of low-level laser therapy (LLLT) with the use of nystatin on in-vitro growth of Candida albicans.