HIV-Associated Thrombotic Thrombocytopenic Purpura in a Virally Suppressed Patient With Normal CD4 Count: A Rare Presentation.

Thrombotic thrombocytopenic purpura (TTP) is a thrombotic process characterized by multiorgan failure secondary to microvascular thrombi comprising platelets and von Willebrand factor. HIV is a known risk factor for TTP. However, patients generally have low CD4+ count during initial presentation or subsequent flare-ups.

Rare Case of Idiopathic Thrombocytopenia Causing Retrobulbar Hemorrhage.

Immune thrombocytopenia purpura (ITP) is defined as a platelet count lower than 100 × 10ˆ9/L, in the absence of known abnormalities in white blood cells, normal hemoglobin with generalized purpuric rash: making it a diagnosis of exclusion.1-2 ITP is due to destruction of platelets in the spleen via autoantibodies, resulting in reduced platelet counts.3 Though rare, ITP is linked with spontaneous retrobulbar hemorrhage (SRH).

A Rare Case of Donor-Derived Renal Cell Carcinoma in a Kidney Transplant Recipient.

BACKGROUND The incidence of renal cell carcinoma (RCC) in transplanted kidneys is reported to be about 0.2%, which makes this case exceedingly rare. Risk factors include older age of the donors, smoking, obesity, and hypertension.

Kidney Histopathology and Prediction of Kidney Failure: A Retrospective Cohort Study.

Rationale & Objective: The use of kidney histopathology for predicting kidney failure is not established. We hypothesized that the use of histopathologic features of kidney biopsy specimens would improve prediction of clinical outcomes made using demographic and clinical variables alone.

Study Design: Retrospective cohort study and development of a clinical prediction model.