Association of podoplanin expression to histopathological grades of oral epithelial dysplasia and oral squamous cell carcinoma.

Objective: To determine the expression of podoplanin, and to correlate it with histopathological grades in oral epithelial dysplasia and oral squamous cell carcinoma cases.

Methods: The retrospective, analytical, cross-sectional study was conducted at the City Laboratory, Peshawar, Pakistan, and comprised specimen block data of histologically diagnosed cases of oral benign lesions, dysplastic lesions and oral squamous cell carcinoma from January 2017 to August 2021. Two sections (4um) were cut from each specimen block for Haematoxylin and Eosin staining and immunohistochemistry.

Depression among Peri- and Post-Menopausal Women during COVID-19 Pandemic in Chandigarh, North India: A Study from Community.

Background: Peri- and post-menopausal women are vulnerable to suffer from mental health problems including depression, anxiety, and stress, which might have increased during the COVID-19 pandemic.

Objective: To estimate the prevalence of depression and associated factors among peri- and post-menopausal women during the COVID-19 pandemic in Chandigarh.

Materials And Methods: A community-based cross-sectional study was conducted among 200 urban peri- and post-menopausal women of age 40-60 years in Chandigarh, from May to June 2021.

Catch-up and Catch-down Growth in Term Healthy Indian Infants From Birth to Two Years: A Prospective Cohort Study.

Background: Catch-up in the first two years of life may help in reducing the growth deficit.

Objective: To study growth pattern of term infants from birth to 2 years, focusing on catch-up and catch-down growth (increase or decrease in z-score >0.67) in weight and length.

Solid lipid nanoparticles containing anti-tubercular drugs attenuate the Mycobacterium marinum infection.

The present study aimed to formulate anti-tubercular drugs (Rifampicin, Isoniazid and Pyrazinamide) loaded solid lipid nanoparticles (ATDs-SLNs) using microemulsion technique for oral administration. Central composite designed (CCD) was applied to study the effect of stearic acid (X), Compritol® 888 ATO (X) and equal ratio of poloxamer 188: sodium taurocholate (% w/w) (X) on particle size, zeta potential and entrapment efficiency. The optimised formulation (SLN) was found to be spherical in shape with mean particle size 187.

Identification of a new Indian camel germplasm by microsatellite markers based genetic diversity and population structure of three camel populations.

Camel invokes fascinating chapter of Indian desert history and is integral component of its ecosystem. Camel population has reached a crisis point after three decades of decline (75%) causing major concern to the policy makers. >28% of Indian camel is not yet characterized.

Changes in oncological outcomes: comparison of the conventional and minimally invasive esophagectomy, a single institution experience.

Minimally invasive esophagectomy is becoming the routine procedure for resectable esophageal cancer. The aim of this retrospective study is to analyze the oncologic adequacy of these two procedures at our Centre. Out of 1252 registered esophageal cancer patients at our institute from 2006 to 2015, 206 patients who underwent a surgical resection with curative intent and a complete medical record were retrospectively evaluated thru hospital medical record system (HIS).

Recent Techniques and Patents on Solid Lipid Nanoparticles as Novel Carrier for Drug Delivery.

The various approaches have been utilized in the treatment of a variety of diseases by applying drug delivery system such as polymeric nanoparticles, self-emulsifying delivery systems, liposomes, microemulsions and micellar solutions. Recently, solid lipid nanoparticles (SLNs), nanostructured lipid carriers (NLCs) and lipid-drug conjugates (LDCs) have been exploited as a carrier of lipophilic and hydrophilic/amphiphilic substances for invasive and non-invasive routes of delivery. SLNs are colloidal drug carrier system and are like nanoemulsion, however, the lipid content in SLNs is solid in nature.

Salvadora persica.

Salvadora persica (kharijal) is a large, well-branched, and evergreen shrub or a tree resembling Salvadora oleoides (meethijal) found in the dry and arid regions of India. Chewing sticks have been used for centuries for tooth cleaning, and are recommended by the World Health Organization in areas where their use is customary. Salvadora persica has enormous reported activities.