Publications by authors named "Khashia Mulbagal"
Article Synopsis
- - A study assessed thyroid dysfunction in asymptomatic women aged 16 to 41 who have experienced miscarriage or subfertility while trying to conceive, involving nearly 20,000 participants across UK hospitals from 2011 to 2016.
- - The study found that 4.8% of women had abnormal thyroid function, with 0.2% having overt hypothyroidism and 0.3% overt hyperthyroidism; notable rates of subclinical hypothyroidism increased significantly when TSH levels were defined more strictly.
- - Factors linked to higher rates of thyroid dysfunction included a BMI of 35.0 kg/m² or higher, Asian ethnicity, and a history of subfertility, while 9.5%
Background: Thyroid peroxidase antibodies are associated with an increased risk of miscarriage and preterm birth, even when thyroid function is normal. Small trials indicate that the use of levothyroxine could reduce the incidence of such adverse outcomes.
Methods: We conducted a double-blind, placebo-controlled trial to investigate whether levothyroxine treatment would increase live-birth rates among euthyroid women who had thyroid peroxidase antibodies and a history of miscarriage or infertility.