Publications by authors named "Kharmoum Saoussane"

Article Synopsis
  • The study focuses on the clinicopathological features and prognosis of placental site trophoblastic tumor (PSTT) and epithelioid trophoblastic tumor (ETT), conducting the largest analysis of these tumors to date using machine learning for treatment assessment and prognostic model development.
  • The research utilized data from the SEER database, employing Cox regression analysis and five machine learning algorithms to predict 5-year survival rates, with the accuracy of these models validated through ROC curve analysis.
  • Results indicated that while survival rates were similar across different tumor types, factors such as metastasis, age, and treatment type significantly influenced prognosis, with the Gradient Boosting classifier being the most accurate in predicting outcomes.
View Article and Find Full Text PDF

Currently, the standard treatment for extremity high-risk soft tissue sarcomas (ESTS) combines surgery and pre- or post-op radiation therapy (RT). In some selected cases, chemotherapy (CT) is incorporated into the therapeutic algorithm as a neoadjuvant approach to enable conservative management. Given the risk of local or metastatic relapse, this paper discusses the potential benefits of CT and RT in high-grade ESTs.

View Article and Find Full Text PDF

Introduction: Oral anticancer therapy is becoming increasingly developed; their prescription has become a common practice in oncology. However, there is a variability and diversity in prescription practice. Its magnitude has been very little studied in scientific literature.

View Article and Find Full Text PDF

Acute chemotherapy-induced lupus erythematosus (ALE) is rare. A few cases have been reported in the literature criminalizing capecitabine, paclitaxel and docetaxel. We report the case of a 64-year old female patient without a history of autoimmune diseases or of drug allergy followed up for invasive ductal carcinoma in the right breast immediately metastatized to the liver and to the lymph nodes.

View Article and Find Full Text PDF

Background: Breast metastasis is fairly uncommon and prognosis is dismal. Breast metastasis might be the first symptom or may occur during the course of other malignancies dominantly arising from the contralateral breast. Leukemia, lung cancer and conjunctival melanoma may spread to the breast.

View Article and Find Full Text PDF

Background. Although some mature cases of teratomas have recently been described in the cervix, they are not commonly found in the uterus, especially in immature forms. An immature uterine teratoma relapsing after surgery as malignant neuroepithelioma has never been reported in the literature.

View Article and Find Full Text PDF

Spontaneous excavation of primary lung cancer is common; however cavitation of metastatic lung lesions is rare and usually confused with benign lesions. In Moroccan context tuberculosis is the first suspected diagnosis of lung excavations. We report a rare case of cavitary lung metastasis of a uterine cervix cancer, treated initially as tuberculosis.

View Article and Find Full Text PDF

Background: Situs inversus totalis represents an unusual anomaly characterized by a mirror-image transposition of the abdominal and thoracic viscera. It often occurs concomitantly with other disorders that make difficult diagnosis and management of abdominal pathology. The relationship between situs inversus totalis and cancer remains unclear.

View Article and Find Full Text PDF