Publications by authors named "Kharitonov R"

The manifestations of Tourette's disease, represent the combination of neurologic and psychopathologic symptomatology. The patients show such manifestations as tics and obsessions while both groups of symptoms are fairly resistant to conservative therapy. The authors describe a case where stereotaxic cryodestruction of the ventrolateral nucleus of the thalamus was applied in addition to the treatment of the patient with medicamentous agents, psychotherapy and measures of social rehabilitation.

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Altogether 700 patients suffering from epilepsy were examined. Of these, 49 patients (7%) were with a history of affective respiratory attacks (ARA) and constituted a catamnestic group. The control group included 110 patients with ARA.

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[Alalic syndromes in deaf children].

Zh Nevropatol Psikhiatr Im S S Korsakova

January 1990

Clinical and experimental psychological investigation of 92 deaf children with various forms of mental dysontogenesis made it possible to single out a clinical group of deaf children with steady speech underdevelopment due to cerebral defects of residual-organic genesis and hereditary etiology. The features of the structure of intellectual defect are shown together with changes in emotionality and personality characteristic of deaf alalics. Singling out the pathognomonic features of intellectual and affective personality spheres can meet the needs of differential diagnosis of alalic syndromes from other clinical forms of mental underdevelopment in children with inherited and early acquired deafness in order to provide an adequate medico-pedagogical++ correction of these disorders.

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A total of 549 epileptic children and 162 healthy children were studied dermatoglyphically. The authors found significant dermatoglyphic differences between the control subjects and patients suffering from epilepsy with a progressive and an unprogressive course. Dermatoglyphic characteristics in the epileptic patients varied in groups with different clinical characteristics (age at the onset of the disease and the duration of the latter, the daily development of paroxysms at the same time, a tendency toward a stable course, the presence of psychic states and the resistance to therapy).

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The effect of dopamine blockers (chlorpromazine and haloperidol) and the dopaminomimetic piribedil on the structure of the breathing cycle was studied under conditions of the clinical employment of the drugs. It was found that piribedil increased the inspiration fraction (IF) in the respiratory cycle whereas neuroleptics diminished it. Twenty-six children with Tourette's syndrome (TS) and 24 with a temporal form of epilepsy were examined.

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The article presents statistical data on the time characteristics of petit mal epilepsy registered in the course of prolonged telemetric EEG recording in 3 epileptic patients in the process of treatment. The time-course of the frequency and also the average and total daily length of attacks during sleep or wakefulness are analyzed. The pattern of the genesis of paroxysms was found to be different: paroxysms were more likely both to arise and stop in sleep than in wakefulness.

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The duration of the R-R cardiointerval (CI) in 13 patients with Tourette's syndrome (TS) aged 9 to 17 years proved to be significantly (+17%; p less than 0.001) longer than in 27 patients of the same age with other neuropsychiatric diagnoses (temporal epilepsy, schizophrenia, neurosis, residual organics) and when compared with the normal values for the respective age (+16.2%; p less than 0.

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On the basis of examining 55 patients with Gilles de la Tourette's syndrome psychic disturbances thought to be not characteristic of the disease before are described. A suggestion on nosological independence of the disease, and on possible participation of the cholinergic systems in the pathogenesis of the ailment is raised. The results of various therapy methods including the comatose one not used in that disease before are presented.

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288 cases of posttraumatic deforming arthrosis of the knee-joint were examined. The further postoperative periodic examinations and checking of the late results of the treatment of 171 patients have proved that the symptoms of the disease are mainly due to the disorders in the knee-joint stability. The obtained data suggest the possibility of a secondary inflammatory origin of pain in deforming arthrosis and witness an important role played by the surgical prevention and correction of the joint instability in clinical remission of th disease.

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A dermatoglyphical study was conducted on 393 children and adolescents suffering from different forms of epilepsy. The group of epileptic patients compared to normals demonstrated more frequent existence of the transversal sulcus, less symmetricity on digital patterns. The authors distinguished correlations between dermatoglyphical features and a form of epilepsy, type of a course and pathogenic forms.

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The aim of the present work is to study the peculiarities of upright position and walking in patients with deforming arthrosis of the knee joint and to make a conclusion as to the possibility of using biomechanical methods for an objective estimate of the efficacy of treatment in such patients. The authors examined 88 patients with deforming arthrosis of various degree of severity and marked pain syndrome. In the examination separate weighing, seismoactography, ichnography and podography were employed.

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The authors followed-up 720 epileptic children who were previously treated in hospitals. The duration of follow-up was from 5-20 years. It was established that at the moment of the study 43.

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