[Panniculitis in patient undergoing treatment for dermatomyositis with methotrexate].

Panniculitis is a rare cutaneous manifestation of dermatomyositis (DM). The appearance of panniculitis during treatment with methotrexate (MTX) is exceptional and has only been described in 3 cases. We report a case of a 50-year-old woman suffering from DM since 1997 who was treated with corticosteroids showing favorable clinical and biological evolution.

TULUP (TUnisian LUPus): a multicentric study of systemic lupus erythematosus in Tunisia.

Aim: Clinical features of systemic lupus erythematosus (SLE) have been described from different geographical regions around the world. However, data from North African countries, including Tunisia, are scarce.

Methods: The aim of this retrospective multicenter study was to analyze demographic, clinical, laboratory features and outcome of SLE in Tunisia throughout 14 Departments of Internal Medicine and to compare them with those of other ethnic and geographic groups.

Contribution of Hla-B51 in the susceptibility and specific clinical features of Behcet's disease in Tunisian patients.

Background: Many researchers have tried to investigate the association of HLA-B51 with the severity and the clinical features of BD with conflicting results.

Methods: We aimed at investigating the association of HLA-B51 with demographical and clinical manifestations as well as the severity of BD, by studying 178 native Tunisian BD patients, fulfilling the International Study group criteria for the BD classification recruited from the Department of Internal Medicine, Rabta Hospital in Tunis and compared with 125 native Tunisian healthy age and sex matching volunteers.

Results: According to our findings, the frequency of HLAB 51 was significantly higher in BD patients than in controls (p<0.

A Rare Cause of Lobular Panniculitis: Munchausen's Syndrome.

We describe a case of a 40-year-old woman who presented with ecchymoses of the right leg and who was found to have lobular panniculitis in biopsy due to Munchausen's Syndrome.

[Shulman syndrome. A report of 4 cases and review of the literature].

The goal of this study is to report four cases of Shulman syndrome with a literature review. Shulman syndrome is a rare disorder recently considered a systemic disease. Our first case shows woody induration of the buttock and trunk with features of morphea.

Tc1/Tc2 ratio in the inflammatory process in patients with Behçet's disease.

Background: Peripheral blood CD8+ T cells expressing interferon gamma and interleukin-4 (IL-4), and lacking CD28 molecules, were responsible for the dynamic interplay between peripheral blood and inflammatory sites.

Introduction: The aim of the current study was to define in Behçet's disease (BD), CD8+ T-cell subsets using CD28 and CD11b monoclonal antibodies, and the characterization of the Tc1/Tc2 ratio and perforin expression.

Methods: Flow cytometry was used for intracytoplasmic cytokines and perforin expression.