Floods accompanied by thunderstorms in developed cities are hazardous, causing damage to infrastructure. To secure infrastructure, it is important to employ an integrated approach, combining remote sensing, GIS and precipitation data. The model was developed based on the estimation of event-based runoff and investigated the relationship between runoff and impervious surfaces.
View Article and Find Full Text PDFPrevious studies highlighted the significance of tailoring alkaline activators (AA) to specific fly ash (FA) sources for optimal properties of geopolymer concrete (GPC). This study examines the influence of various AA's properties on mechanical properties and microstructures of local low-calcium FA-based GPC under varying curing conditions. A comprehensive investigation consists of several factors such as NaOH molarities (10 M, 12 M, 14 M, 16 M), ratios (1.
View Article and Find Full Text PDFIntroduction: Proton pump inhibitors (PPIs) are effective drugs used for multiple gastrointestinal complications. They are commonly used in both hospitalised and outpatients. However, little is known about its utilisation pattern in ambulatory patients.
View Article and Find Full Text PDFThe advancement of artificial intelligence (AI) and the ubiquity of social media have become transformative agents in contemporary educational ecosystems. The spotlight of this inquiry focuses on the nexus between AI and social media usage in relation to academic performance and mental well-being, and the role of smart learning in facilitating these relationships. Using partial least squares-structural equation modeling (PLS-SEM) on a sample of 401 Chinese university students.
View Article and Find Full Text PDFBACKGROUND Cosmetics are applied topically to enhance appearance and are commonly used by women of all ages. Cosmetics contain many chemical agents, but the incidence of adverse reactions is low, possibly due to underreporting. This questionnaire-based study included 392 women to evaluate information on the types of cosmetics purchased between December 2018 and March 2019, their use by the women surveyed, and their associated adverse events.
View Article and Find Full Text PDFAtrial fibrillation (AF) is a common arrhythmia associated with significant morbidity and mortality. The optimal approach to managing AF, specifically rate control versus rhythm control, remains a topic of debate in clinical practice. This systematic review aims to compare the rate control and rhythm control strategies based on their clinical outcomes, quality of life, and adverse events associated with them.
View Article and Find Full Text PDFWith the advent of modern antiretroviral therapy (ART), human immunodeficiency virus (HIV) infection has been modified into a chronic manageable condition, prolonging the lifespan of people living with HIV (PLHIV). This has resulted in an increased non-AIDS-related morbidity in the HIV-infected population. Our aim is to study the role of contemporary ART in tackling the risk of atherosclerosis and cardiovascular disease (CVD) in PLHIV.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
December 2023
Environment has detrimental effects on economic activity and human survival. Climate change is increasingly conducive to natural disasters, epidemics, social conflicts, food security, financial shocks, economic hardships, and life subsistence. In pursuit of this issue, this study empirically investigates the effects in outcome variable CO provoked by independent variables governance, technological innovation, renewable energy, economic growth, and economic policy uncertainty in APEC economies.
View Article and Find Full Text PDFPurpose: Proton pump inhibitors (PPIs) are widely used to treat a range of gastrointestinal diseases around the world. Long-term use of PPIs has been associated to a variety of undesirable effects. Although short-term therapy has been shown to have little or no effect on endocrine hormone in women, however, its long-term safety has received little attention.
View Article and Find Full Text PDFIntegrating nanotechnology in dielectric fluid significantly inhibits losses and boosts overall dielectric fluid performance. There has been research done on the effects of introducing various nanoparticles, such as titania, alumina, silica nanodiamonds, etc. In this paper, a novel nanoparticle, Ceria (CeO), has been used, and its properties were examined using the FTIR (Fourier Transform Infrared) spectrum, the XRD (X-ray Diffraction) spectrum, the SEM (Scanning Electron Microscopy), and the TEM (Transmission Electron Microscopy).
View Article and Find Full Text PDFObjectives: Osteoarthritis (OA) causes long-term pain and disorders of lower extremities. Paracetamol is the drug of choice; however, NSAIDs, opioids and steroids are frequently employed in the symptomatic relief of OA. The prescribing of multiple analgesics leads to potential drug-drug interactions (pDDIs).
View Article and Find Full Text PDFIn the contemporary world, the importance of natural resources is increasing day by day especially due to extraordinary circumstances, i.e., COVID-19 and global conflicts.
View Article and Find Full Text PDFAims: Glucagon-like peptide 1 receptor agonists (GLP-1RA) improve glycemic control and promote weight loss in type 2 diabetes (DM2) and obesity. We identified studies describing the metabolic benefits of GLP-1RA in end-staged kidney disease (ESKD) and kidney transplantation.
Data Synthesis: We searched for randomized controlled trials (RCTs) and observational studies that investigated the metabolic benefits of GLP-1RA in ESKD and kidney transplantation.
Proton pump inhibitors (PPI) are commonly prescribed medications for a variety of gastrointestinal disorders around the globe. Long-term utilization of proton pump inhibitors is linked with different adverse events. Although, short-term therapy has been demonstrated to have little or no impact on endocrine hormones in men, yet its safety with long-term use has poorly been studied.
View Article and Find Full Text PDFSensors play a significant role in modern technologies and devices used in industries, hospitals, healthcare, nanotechnology, astronomy, and meteorology. Sensors based upon nanostructured materials have gained special attention due to their high sensitivity, precision accuracy, and feasibility. This review discusses the fabrication of graphene-based biosensors and gas sensors, which have highly efficient performance.
View Article and Find Full Text PDFAdvanced anodic SnO nanoporous structures decorated with CuO nanoparticles (NPs) were employed for creatinine detection. Anodization of electropolished Sn sheets in 0.3 M aqueous oxalic acid electrolyte under continuous stirring produced complete open top, crack-free, and smooth SnO nanoporous structures.
View Article and Find Full Text PDFThe Emirate of Abu Dhabi has relied on groundwater as a source of fresh water for several decades, which has resulted in the deterioration of non-renewable groundwater aquifers. This has led to the installation of desalination plants for fresh water supply. This research aims to increase strategic water reserves in the eastern district of Abu Dhabi by analyzing the best locations for aquifer storage and recovery (ASR).
View Article and Find Full Text PDFBackground: The storage of antimicrobials at home is frequently in-practice in various developing countries, resulting an irrational use, antibiotic resistance, and toxicities. This condition may worsen more in conflict zones where health facilities are limited. This study aimed to determine the storage and use of leftover antibiotics among households (HHs) along with knowledge and awareness about antibiotics and antibiotic resistance (ABR).
View Article and Find Full Text PDFFloods are among the devastating types of disasters in terms of human life, social and financial losses. Authoritative data from flood gauges are scarce in arid regions because of the specific type of dry climate that dysfunctions these measuring devices. Hence, social media data could be a useful tool in this case, where a wealth of information is available online.
View Article and Find Full Text PDFCurr Med Res Opin
April 2022
Background: Spontaneous Adverse drug reactions (ADRs) reporting is a cornerstone for a successful pharmacovigilance program as under-reporting of ADRs remains a major issue around the globe. The current study aimed to assess the knowledge attitude and practices of health care professionals regarding pharmacovigilance along with barriers and factors to encourage ADR reporting at tertiary care hospitals of Khyber-Pakhtunkhwa, Pakistan.
Methods: A questionnaire-based cross-sectional survey was conducted, using the convenience sampling method to collect the data from doctors, nurses, and pharmacists working in seven tertiary care hospitals from seven districts of Khyber-Pakhtunkhwa province, Pakistan, between July 2019 and March 2020.
Nanotechnology is one of the emerging fields of the 21st Century. Many new devices and patentable technology is based on nanomaterials (NMs). One of the dominant factors in the use of nanomaterials and their applications in various fields is the synthesis and growth mechanism of nanostructures and nanomaterials.
View Article and Find Full Text PDFBackground: Perianal fistula (PAF), a complication of Crohn's disease (CD), is associated with substantial economic costs and poor prognosis. We determined prevalence of PAF CD in the United States and compared costs and health care resource utilization (HRU) of PAF CD patients with matched non-PAF CD patients.
Methods: This was a retrospective cohort study of claims data from the IBM MarketScan Commercial Database from October 1, 2015, to September 30, 2018.
In recent years, emerging two-dimensional (2D) platinum diselenide (PtSe) has quickly attracted the attention of the research community due to its novel physical and chemical properties. For the past few years, increasing research achievements on 2D PtSe have been reported toward the fundamental science and various potential applications of PtSe. In this review, the properties and structure characteristics of 2D PtSe are discussed at first.
View Article and Find Full Text PDFVenetoclax is a small molecule inhibitor of the prosurvival protein BCL-2 that has gained market approval in BCL-2-dependent hematologic cancers including chronic lymphocytic leukemia and acute myeloid leukemia. Neuroblastoma is a heterogenous pediatric cancer with a 5-year survival rate of less than 50% for high-risk patients, which includes nearly all cases with amplified We previously demonstrated that venetoclax is active in -amplified neuroblastoma but has limited single-agent activity in most models, presumably the result of other pro-survival BCL-2 family protein expression or insufficient prodeath protein mobilization. As the relative tolerability of venetoclax makes it amenable to combining with other therapies, we evaluated the sensitivity of -amplified neuroblastoma models to rational combinations of venetoclax with agents that have both mechanistic complementarity and active clinical programs.
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