Publications by authors named "Khan Osama"

Pancreatic cancer (PC) manifests as a highly aggressive neoplastic growth, ranking as the fourth major contributor to cancer-related mortality in the United States. Despite sustained efforts, the incidence of PC is projected to rise, and the mortality rate has seen only a marginal reduction over time. A mere 15% of pancreatic cancer cases are deemed resectable upon presentation, explaining the notably low 5-year survival rate associated with this malignancy.

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Article Synopsis
  • Patients awaiting heart transplants often require colonoscopies due to bleeding or screening needs, but there's limited research on the safety of these procedures for individuals on inotropic medications or mechanical circulatory support.
  • A study was conducted from 2015 to 2021 with 92 heart failure patients undergoing colonoscopy while on advanced heart failure therapies, such as inotropes or mechanical devices.
  • Results indicated that the most common reason for colonoscopy was cancer screening, with significant findings including 8% of screening procedures revealing advanced adenomas and 17% of bleeding-related colonoscopies identifying sources needing intervention, but no major complications related to anesthesia were reported.
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In past years, concentrated solar power (CSP) with an energy backup system has been a unique renewable energy utilization system among intermittent renewable energy systems. It could allow a CSP plant to operate as a base load system in the future. This paper simulates a solar power plant for 1 MWe.

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Background: Although the concept of telehealth is of great interest globally, its potential has not yet been realized in Pakistan. It is therefore essential to explore the perspectives of stakeholders on the technology, particularly for mental health, to be able to increase and improve its use.

Aim: To assess the perceptions and experiences of patients receiving tele-mental health services, including telepsychiatry and tele-psychotherapy, in Pakistan.

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The underutilization of digestate-derived polymers presents a pressing environmental concern as these valuable materials, derived from anaerobic digestion processes, remain largely unused, contributing to pollution and environmental degradation when left unutilized. This study explores the recovery and utilization of biodegradable polymers from biomass anaerobic digestate to enhance the performance of solar photovoltaic (PV) cells while promoting environmental sustainability. The anaerobic digestion process generates organic residues rich in biodegradable materials, often considered waste.

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Owing to its natural and rich advantages, exploration of solar energy technology has become increasingly popular in recent years to counter the growing crude oil prices. However, its universal adoption is still limited, not only due to environmental restrictions but also due to lower overall efficiency. Rankine cycle is optimised to conduct 4-E (Exergy, Energy, Economic and Ecological) analysis.

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Landfill leachates contain harmful substances viz. chemicals, heavy metals, and pathogens, that pose a threat to human health and the environment. Unattended leachate can also cause ground water contamination, soil pollution and air pollution.

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The study presently conducted focused on analyzing a solar-powered desalination setup that had a double slope. It can recycle blackish water into drinking water with solar energy. Not only does this result in a significant decrease in carbon emissions but it also represents an environmentally beneficial alternative that is particularly suited for arid locations that are lacking of electrical infrastructure.

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Integrating nanoparticles in waste oil-derived biodiesel can revolutionize its performance in internal combustion engines, making it a promising fuel for the future. Nanoparticles act as combustion catalysts, enhancing combustion efficiency, reducing emissions, and improving fuel economy. This study employed a comprehensive approach, incorporating both quantitative and qualitative analyses, to investigate the influence of selected input parameters on the performance and exhaust characteristics of biodiesel engines.

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Achalasia is a rare esophageal motility disorder that leads to dysphagia, regurgitation, and several other symptoms. While the etiology of achalasia is not completely understood, studies have suggested an immune reaction to viral infections, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), as a potential cause. Here, we present a case report of a previously healthy 38-year-old male who presented to the emergency room with severe shortness of breath, recurrent vomiting, and dry cough, that had progressively worsened over five days.

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Thermal losses through weak building envelope is responsible for global current energy crises. Application of artificial intelligence and drone setups in green buildings can help in providing the sustainable solution the world is striving for years. The contemporary research incorporates a novel concept of measuring the wearing thermal resistances in the building envelope with the aid of a drone system.

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Since the discovery of petrol-based products, a surge in energy-requiring equipment has been established across the world. Recent depletion of the existing crude oil resources has motivated researchers to opt for and analyze potential fuels that could potentially provide a cost-effective and sustainable solution. The current study selects a waste plant known as through which biodiesel is generated, and its blends are tested in diesel engines for feasibility.

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Papillary renal cell carcinoma comprises around 15% of all renal cell carcinomas. Patients are usually asymptomatic, and 25 percent of individuals have advanced locoregional disease at presentation. Papillary renal cell carcinoma presenting as a huge abdominal cystic mass is uncommon and is reported rarely in literature.

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Background: Colorectal cancer is the largest cause of mortality in patients admitted to any Gastroenterology units. Diagnostic colonoscopy is a valuable tool for the disease's diagnosis and proper treatment but its compliance has been historically low. Our main objective was to find out social, cultural, and psychological barriers among those patients who finally did not show up for their colonoscopy appointment and, make a comparative analysis with those who did.

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Systemic lupus erythematosus (SLE) is a complex autoimmune disease with multisystem involvement. It is multifactorial and involves epigenetic, genetic, ecological, and environmental factors. Primarily it leads to activation of both innate and adaptive immunity, which consequently leads to autoreactive B cell activation by T cells and leads to immune complexes deposition in tissues leading to an autoimmune cascade that may be limited to the single organ or can cause a widespread systemic involvement.

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There is a pressing need to accelerate the development of advanced technologies to prevent Coronavirus in large gatherings. The present system is an integration of tunnel disinfectant spray system and solar setup which utilises the solar energy to power a pump which pushes the required amount of chemical mixture into the nozzles of the spray system in order to eliminate any incoming virus or bacteria on the clothes of a particular person without wetting it. Data was gathered for a mall in New Delhi related to occupancy levels before and after lockdown.

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We report the first time-synchronized protocol stack running on a crystal-free device. We use an early prototype of the Single-Chip micro Mote, SCµM, a single-chip 2×3 mm 2 mote-on-a-chip, which features an ARM Cortex-M0 micro-controller and an IEEE802.15.

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Background: After the emergence of new influenza viruses, the morbidity and mortality of viral pneumonia have received a great attention.

Objectives: The objective of this study is to describe the epidemiologic, clinical and laboratory changes, and outcomes of viral pneumonia caused by influenza and the Middle East respiratory syndrome-coronavirus (MERS-CoV) infections.

Methods: In a retrospective cohort study, the medical records of all patients diagnosed with viral pneumonia at Prince Sultan Military Medical City, Riyadh, Saudi Arabia, during the period from January 2012 to December 2015 were screened.

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Objective: To determine the association between passive smoking and chronic obstructive pulmonary disease.

Methods: The cross-sectional study was conducted from October 2015 to March 2016 at the Ojha campus of Dow University Hospital, Karachi, and comprised individuals who denied past or current active smoking and exposure to bio-mass fuel. The subjects were attendants coming with patients, hospital staff, faculty and medical students aged 15-64 years.

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In present study, biodiesel was produced from landfill waste-derived oil by chemical transesterification process, to evaluate its potential as a renewable energy source for the first time. The free fatty acid percentage (FFA) in landfill waste oil is considered to be high, which was reduced by treating it with two different acids as catalyst, muriatic acid and phosphoric acid, in order to build a comparison between fatty acid methyl ester (FAME) contents. Further, it was treated with a base catalyst potassium hydroxide (KOH) to produce the final product.

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Article Synopsis
  • Football is a globally popular sport, but it is associated with a high rate of gonarthrosis (knee osteoarthritis) among players.
  • This elevated risk is attributed mainly to injuries in the meniscus and anterior cruciate ligament (ACL), often leading to surgeries.
  • Knee injuries are the most common type among football players and contribute significantly to long-term knee problems after the sport.
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Epilepsy is common disorder that affects over 50 million people worldwide. Birds remain a promising yet largely under-explored model of epilepsy. This study reports the comparison of the response of two species of birds, Australian Parrots (APs) and Sparrows (SPs), to a pro-epileptic drug, Pentylenetetrazole (PTZ).

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Objective: Early detection of Chronic Obstructive Pulmonary Disease in apparently healthy attendants of tertiary care hospital and assessment of its severity.

Study Design: Cross-sectional, observational study.

Place And Duration Of Study: Study was conducted from January 2015 to July 2015 at Dow University Hospital, Ojha campus.

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Giant cell arteritis (GCA) or Temporal arteritis (TA) is an autoimmune disease and the most common type of vasculitis in the elderly. It causes inflammation of the medium and large arteries in the upper part of the body. GCA is an under-recognized cause of  head aches in the elderly, especially when it presents itself with atypical features, resulting in delayed or incorrect diagnosis.

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Objective: To determine frequency of substance abuse and the commonest substance of abuse among medical and non-medical undergraduates.

Study Design: Survey report.

Place And Duration Of Study: Dow International Medical College, Karachi, from June 2012 to August 2012.

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