Proc Natl Acad Sci U S A
February 2025
Measurement literacy is required for strong scientific reasoning, effective experimental design, conceptual and empirical validation of measurement quantities, and the intelligible interpretation of error in theory construction. This discourse examines how issues in measurement are posed and resolved and addresses potential misunderstandings. Examples drawn from across the sciences are used to show that measurement literacy promotes the goals of scientific discourse and provides the necessary foundation for carving out perspectives and carrying out interventions in science.
View Article and Find Full Text PDFIntroduction: The integration of artificial intelligence (AI) into healthcare introduces innovative possibilities but raises ethical, legal and professional concerns. Assessing the performance of AI in core components of the United States Medical Licensing Examination (USMLE), such as communication skills, ethics, empathy and professionalism, is crucial. This study evaluates how well ChatGPT versions 3.
View Article and Find Full Text PDFResting state networks (RSNs) of the brain are characterized as correlated spontaneous time-varying fluctuations in the absence of goal-directed tasks. These networks can be local or large-scale spanning the brain. The study of the spatiotemporal properties of such networks has helped understand the brain's fundamental functional organization under healthy and diseased states.
View Article and Find Full Text PDFObjective: Alcohol use disorder carries major effects shown to limit social support, increase recovery times, and lead to a higher incidence of surgical complications. This retrospective cohort study investigated the influence of AUD on perioperative outcomes and adverse events after spinal fusions in the largest sample size to date and spanning 11 years.
Methods: Data for adult (>18 years old) patients who underwent a spinal fusion as their primary surgery were identified from the Nationwide Inpatient Sample (NIS) database for the years 2009-2020.
J Coll Physicians Surg Pak
January 2025
Objective: To compare the closed reduction approach with open reduction (transparotid approach) in the management of condylar fractures for parameters such as postoperative facial nerve injury, trismus, and malocclusion.
Study Design: An analytical comparative study. Place and Duration of the Study: Department of Oral and Maxillofacial Surgery, The Armed Forces Institute of Dentistry, Rawalpindi, Pakistan, from 10th January 2022 to 1st October 2023.
Diabetes, a chronic metabolic condition characterised by persistently high blood sugar levels, necessitates early detection to mitigate its risks. Inadequate dietary choices can contribute to various health complications, emphasising the importance of personalised nutrition interventions. However, real-time selection of diets tailored to individual nutritional needs is challenging because of the intricate nature of foods and the abundance of dietary sources.
View Article and Find Full Text PDFBackground Gallbladder carcinoma (GBC) is a rare but highly aggressive malignancy, often discovered incidentally during cholecystectomy for symptomatic cholelithiasis. Despite significant geographic variation, the association between gallstones and GBC is well-documented, with chronic inflammation from gallstones potentially contributing to carcinogenesis. Objective This study aims to determine the prevalence of incidental GBC in patients undergoing cholecystectomy for symptomatic cholelithiasis at a tertiary care hospital in Peshawar, Pakistan.
View Article and Find Full Text PDFOn 11 February 2020, the prevalent outbreak of COVID-19, a coronavirus illness, was declared a global pandemic. Since then, nearly seven million people have died and over 765 million confirmed cases of COVID-19 have been reported. The goal of this study is to develop a diagnostic tool for detecting COVID-19 infections more efficiently.
View Article and Find Full Text PDFCurr Opin Ophthalmol
December 2024
Purpose Of Review: To describe recent evidence regarding surgical techniques for secondary scleral fixation of intraocular lenses (IOLs), with attention to information most relevant to the surgical practice of vitreoretinal surgeons.
Recent Findings: Recent studies have reported favorable outcomes in patients treated with scleral fixation of IOLs using Gore-Tex suture and flanged intrascleral haptic fixation (ISHF). ISHF can be achieved using trocar-cannulas or double needle-based techniques.
, an antagonistic bacterium, was utilized to develop antimicrobial edible films based on whey protein concentrate. This study employed a Taguchi test (3 × 3) to evaluate the impact of temperature, pH, and protein concentration on film properties. Optimal growth of occurred at 6% (/) protein and pH 9.
View Article and Find Full Text PDFObjective: The escalating incidence of de novo spinal infections poses a substantial neurological impact on patients. This has prompted a growing interest in discerning which patients would derive greater benefit from medical as opposed to surgical management of these occurrences. The authors assessed the predictive applicability of the Spinal Infection Treatment Evaluation (SITE) score in discerning between surgical intervention and medical management.
View Article and Find Full Text PDFWomen's career progression and empowerment in STEM (science, technology, engineering, and mathematics) sectors are critical to attaining SDG 5: Gender Equality because they promote equal access to education, job prospects, and leadership roles, building a more inclusive and equitable society. The purpose of this study is to look into the impact of perceived overqualification (POQ) on career anxiety and career decidedness (CD) among women in STEM disciplines while also considering the function of career identity (CI) and leadership support. With a total sample size of 1,045 participants, two distinct investigations were conducted, one in the educational field (N = 530) and one in an industry setting (N = 515 time-lag).
View Article and Find Full Text PDFBackground Soccer, a globally popular sport, demands a complex interplay between physical attributes, including speed, agility, power, and endurance. Although lower-body strength and power are often emphasized, the role of upper-body strength, particularly shoulder strength, remains less explored. Given the importance of upper-body movements in activities such as heading, shooting, and defending, understanding the relationship between shoulder strength and soccer performance is crucial.
View Article and Find Full Text PDFBackground: It has been hypothesized that both atrial fibrillation (AF) and medications for AF are poorly tolerated in athletes.
Objective: The purpose of this study was to determine the impact of AF and AF treatments on sports performance.
Methods: An Internet-based survey, initiated via StopAfib.
In order to recover and effectively remove beryllium from beryllium-containing wastewater and relieve the environmental pressure caused by waste batteries. In this study, the gel material was synthesized based on the modified graphite material separated from the waste battery, and the graphite-@chitosan composite gel (CWBG@CH) was designed and synthesized. Interestingly, CWBG@CH has a maximum fitted adsorption capacity (Q) of 83.
View Article and Find Full Text PDFPurpose: Limited data exists evaluating same-day discharge for pediatric Nuss procedure; most being single-center studies. Our analysis, using the NSQIP-P registry, aimed to assess if same-day discharge for the Nuss procedure influenced post-operative outcomes.
Methods: The NSQIP-P database (2017-2022) identified patients who underwent the Nuss procedure.
An integrated approach using geophysical and geospatial techniques was employed to model the surface and subsurface water-bearing strata and assess aquifer vulnerability in the Sehnsa town, Kotli district, State of Azad Kashmir, Pakistan. The inadequate scientific studies in the hilly terrain with such complex geological conditions has led to the failure of the boreholes for groundwater extraction. For the evaluation of groundwater potential and subsurface lithology, 30 vertical electrical soundings (VES) stations utilizing the Schlumberger electrode configuration were completed, modeled and analyzed spatially.
View Article and Find Full Text PDFCortical cholinergic projections originate from subregions of the basal forebrain (BF). To examine its organization in humans, we computed multimodal gradients of BF connectivity by combining 7 T diffusion and resting state functional MRI. Moving from anteromedial to posterolateral BF, we observe reduced tethering between structural and functional connectivity gradients, with the lowest tethering in the nucleus basalis of Meynert.
View Article and Find Full Text PDFStudy Design: Cross-sectional study.
Objectives: This study's goal is to report whether Magnetization Transfer Ratio (MTR) can evaluate the severity of white matter (WM) injury in degenerative cervical myelopathy (DCM).
Setting: Laureate Institute of Brain Research, USA; Department of Neurosurgery, University of Oklahoma Health Sciences Center, USA.
Background And Objective: Total Knee Arthroplasty (TKA) has proven highly effective in improving quality of life for patients with severe knee conditions. Despite advancements, surgical complications such as periprosthetic joint infections (PJIs) pose risks. The potential predictive value of pre- and post-operative inflammatory markers like neutrophil-to-lymphocyte ratio (NLR), D-dimer, and albumin levels on surgical outcomes is garnering attention.
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