Predictors of Human Papillomavirus (HPV) Vaccine Acceptability Among Physicians, Their Knowledge on Cervical Cancer, and Factors Influencing Their Decision to Recommend It.

Introduction: In Saudi Arabia, the HPV vaccine is administered to young females through school-based immunization programs; however, the program's efficacy depends on parental consent, with physicians acting as primary determinants in parental decision-making regarding HPV vaccination.

Methods: In this cross-sectional study, we recruited 128 physicians and assessed their knowledge and attitudes toward cervical cancer, HPV, and the HPV vaccine, and unraveled predictors of HPV vaccine acceptability and factors that would influence recommending the vaccine.

Results: Although the major factor that influenced recommending the vaccine negatively was the fear of vaccine side effects, a positive influence of the physician's personal reading (91%), recommendations from colleagues (88%), and government directives (87%) provided reassurance and increased confidence in recommending the vaccine.

Factors influencing human papillomavirus vaccine uptake among parents and teachers of schoolgirls in Saudi Arabia: a cross-sectional study.

Introduction: Cervical cancer is a highly prevalent disease among women worldwide. However, the advent of a vaccine against HPV, the main cause of the disease, has prevented its spread. The acceptability of the HPV vaccine to different sectors of the Saudi community has yet to be clarified.

Lung nodule localization and size estimation on chest tomosynthesis.

Purpose: We aim to investigate the localization, visibility, and measurement of lung nodules in digital chest tomosynthesis (DTS).

Approach: Computed tomography (CT), maximum intensity projections (CT-MIP) (transaxial versus coronal orientation), and computer-aided detection (CAD) were used as location reference, and inter- and intra-observer agreement regarding lung nodule size was assessed. Five radiologists analyzed DTS and CT images from 24 participants with lung , focusing on lung nodule localization, visibility, and measurement on DTS.

A Bayesian model calibration framework for stochastic compartmental models with both time-varying and time-invariant parameters.

We consider state and parameter estimation for compartmental models having both time-varying and time-invariant parameters. In this manuscript, we first detail a general Bayesian computational framework as a continuation of our previous work. Subsequently, this framework is specifically tailored to the susceptible-infectious-removed (SIR) model which describes a basic mechanism for the spread of infectious diseases through a system of coupled nonlinear differential equations.

Restrictive Spirometric Pattern and Preserved Ratio Impaired Spirometry in a Population Aged 50-64 Years.

Knowledge regarding the prevalence and shared and unique characteristics of the restrictive spirometric pattern (RSP) and preserved ratio impaired spirometry (PRISm) is lacking for a general population investigated with post-bronchodilator spirometry and computed tomography of the lungs. To investigate shared and unique features for RSP and PRISm. In the Swedish CArdioPulmonary bioImage Study (SCAPIS), a general population sample of 28,555 people aged 50-64 years (including 14,558 never-smokers) was assessed.

Evaluating the benefit of virtual surgical planning on bony union rates in head and neck reconstructive surgery.

Objectives: Virtual surgical planning (VSP) has gained acceptance because of its benefits in obtaining adequate resection, achieving cephalometric accuracy, and reducing operative time. The aim of this study is to compare the rate of union between VSP and free-hand surgery (FHS), identify predictors of non-union and evaluate the difference in operative time.

Methods: Post-operative CT were retrospectively reviewed for 123 patients who underwent maxillary or mandibular reconstruction between 2014 and 2021 using either VSP or FHS.

Learning analytics for enhanced professional capital development: a systematic review.

Background/motivation: This article presents a systematic review aimed at examining the utilization of learning analytics (LA) to enhance teachers' professional capital.

Aim: The study focuses on three primary research questions: (1) exploring the characteristics and approaches of LA in professional capital, (2) investigating suggestions from LA for assessing and improving professional capital, and (3) examining variables studied in enhancing the most intricate dimension of professional capital using LA.

Methodology: To address the research objectives, a systematic review was conducted focusing on the key concepts "learning analytics" and "professional capital.

Genome Characterisation of Invasive in Pregnancy: The Noticeable Placental Tissue Tropism Is Distributed across the Species Rather Than Linked with Capsulation or Particular Clones.

Pregnancy is associated with a 5-26 times increased risk of invasive infection and subsequent adverse pregnancy outcomes. Incidence rate and outcome are published in some regions, but the characterisation of bacterial isolates is limited. We performed comparative genomic analyses of isolates from 12 pregnancy-associated cases, cultured from maternal bacteraemia in pregnancy (nine), postpartum bacteraemia (one), neonatal bacteraemia (one), and placental tissue (one).

Acylated ghrelin suppresses doxorubicin-induced testicular damage and improves sperm parameters in rats via activation of Nrf2 and mammalian target of rapamycin.

Background: Exogenous administration of acylated ghrelin (AG) afforded reproductive protective effect in several animal models but not in those treated with doxorubicin (DOX). This study evaluated the protective effect of AG against DOX-induced testicular damage and impairment in sperm parameters in rats and examined the potential mechanisms of action.

Materials And Methods: Adult male rats were divided into five groups (n = 8/each) as control, control + AG (40 nmol/kg/day; subcutaneous), DOX (10 mg/kg/day 1; intraperitoneal [i.

Early T-Cell Precursor Leukemia: A High-Risk Subtype of Acute Lymphoblastic Leukemia, Single Center Experience in Jordan.

Background And Objectives: Early T-cell precursor (ETP) acute lymphoblastic leukemia/lymphoma (ALL/LBL) is a newly recognized entity of T-lymphoblastic leukemia/lymphoma. The optimal therapeutic approaches to adult patients are poorly studied.

Patients And Methods: We compared the outcomes of adult's patents with ETP-ALL/LBL who received frontline chemotherapy regimens with other T-ALL/LBL immunophenotypic subtypes.

Endovascular aneurysm repair of aortocaval fistula presenting with lower limb edema: A case report.

Aortocaval fistula (ACF) due to a ruptured abdominal aortic aneurysm is an uncommon medical condition that can be fatal if not diagnosed. ACF has several atypical signs and symptoms, making it challenging to diagnose, and an early diagnosis notably improves outcomes. We report a case of a 64-year-old man presenting with a 1-day history of lower back pain, hypotension, and lower limb edema.

Unveiling the Culprit: Candida-Induced Spondylodiscitis Following SARS-CoV-2 Infection.

We present a case of a 57-year-old male patient with a history of prolonged intensive care unit (ICU) stay for coronavirus disease 2019 (COVID-19) who developed fungal spondylodiscitis, a rare complication. The patient initially presented complaining of respiratory symptoms and was subsequently treated with tocilizumab, remdesivir, enoxaparin, and dexamethasone. Following ICU discharge, he experienced recurrent infections, including extended-spectrum beta-lactamase urinary tract infection.

Assessing disparities in medical students' knowledge and attitude about monkeypox: a cross-sectional study of 27 countries across three continents.

Background And Aims: The recent monkeypox (Mpox) outbreak confirmed by the World Health Organization (WHO) underscores the importance of evaluating the knowledge and attitude of medical students toward emerging diseases, given their potential roles as healthcare professionals and sources of public information during outbreaks. This study aimed to assess medical students' knowledge and attitude about Mpox and to identify factors affecting their level of knowledge and attitude in low-income and high-income countries.

Methods: A cross-sectional study was conducted on 11,919 medical students from 27 countries.

Corrigendum: Factors influencing participation in COVID-19 clinical trials: a multinational study.

[This corrects the article DOI: 10.3389/fmed.2021.

Learning analytics in support of inclusiveness and disabled students: a systematic review.

This article maps considerations of inclusiveness and support for students with disabilities by reviewing articles within the field of learning analytics. The study involved a PRISMA-informed systematic review of two popular digital libraries, namely Clarivate's Web of Science, and Elsevier's Scopus for peer-reviewed journal articles and conference proceedings. A final corpus of 26 articles was analysed.

Spontaneous activity of specific C-nociceptor subtypes from diabetic patients and mice: Involvement of reactive dicarbonyl compounds and (sensitized) transient receptor potential channel A1.

Background: Diabetic metabolism causes changes of the chemical milieu including accumulation of reactive carbonyl species, for example, methylglyoxal (MGO). MGO activates chemosensitive TRPA1 on nociceptors, but the contribution to neuronal pathophysiology causing pain and hyperalgesia in diabetic neuropathy is not fully understood.

Methods: We employed single-nerve-fiber recordings in type 2 diabetes patients with (spDN) and without cutaneous pain (DN) and in streptozotocin-diabetic and healthy mice.

Reduction in Door-to-Groin Puncture Time for Endovascular Treatment in Acute Ischemic Stroke Patients With Large Vessel Occlusion.

Background The outcome of mechanical thrombectomy for large vessel occlusion (LVO) in patients with acute ischemic stroke (AIS) is time-dependent. In the current stroke workflow, the pre-hospital delay is one of the most common reasons for an increase in door-to-groin puncture time (DGPT). In the present study, we sought to compare the difference in (DGPT) before and after the implementation of the Ventura Emergent Large Vessel Occlusion Score (VES) protocol for LVO.

Medication errors in neonatal intensive care units: a multicenter qualitative study in the Palestinian practice.

Background: Neonatal intensive care units are high-risk settings where medication errors can occur and cause harm to this fragile segment of patients. This multicenter qualitative study was conducted to describe medication errors that occurred in neonatal intensive care units in Palestine from the perspectives of healthcare providers.

Methods: This exploratory multicenter qualitative study was conducted and reported in adherence to the consolidated criteria for reporting qualitative research checklist.

Resolute onyx stent more effective than wingspan stent at preventing procedural complications and long-term restenosis.

Background And Purpose: Angioplasty and stenting is a treatment option for patients with medically refractory symptomatic intracranial atherosclerotic disease (sICAD). Currently the Wingspan Stent System (WSS) is the only FDA approved device for this indication. We find the Resolute (R) Onyx Stent, a drug-eluting balloon mounted stent (DES), a better alternative to the WSS for treatment of sICAD.

Maximising access to timely trauma care across population of Karachi and its districts: a geospatial approach to develop a trauma care network.

Objectives: To develop and propose a cost-effective trauma care network for Karachi, Pakistan, by calculating maximum timely trauma care (TTC) coverage achieved with the addition of potential designated private and public level 1 and level 2 trauma centres (TCs).

Setting: A lower middle-income country metropolis, Karachi is Pakistan's largest city with a population of 16 million and a total of 56 hospitals as per government registry data.

Participants: 41 potential TCs selected using a two-level, contextually-relevant TC designation criteria adapted from various international guidelines.

What Does Twitter Say About Self-Regulated Learning? Mapping Tweets From 2011 to 2021.

Social network services such as Twitter are important venues that can be used as rich data sources to mine public opinions about various topics. In this study, we used Twitter to collect data on one of the most growing theories in education, namely Self-Regulated Learning (SRL) and carry out further analysis to investigate What Twitter says about SRL? This work uses three main analysis methods, descriptive, topic modeling, and geocoding analysis. The searched and collected dataset consists of a large volume of relevant SRL tweets equal to 54,070 tweets between 2011 and 2021.

Comprehensive compartmental model and calibration algorithm for the study of clinical implications of the population-level spread of COVID-19: a study protocol.

Introduction: The complex dynamics of the coronavirus disease 2019 (COVID-19) pandemic has made obtaining reliable long-term forecasts of the disease progression difficult. Simple mechanistic models with deterministic parameters are useful for short-term predictions but have ultimately been unsuccessful in extrapolating the trajectory of the pandemic because of unmodelled dynamics and the unrealistic level of certainty that is assumed in the predictions.

Methods And Analysis: We propose a 22-compartment epidemiological model that includes compartments not previously considered concurrently, to account for the effects of vaccination, asymptomatic individuals, inadequate access to hospital care, post-acute COVID-19 and recovery with long-term health complications.

Lumbar vertebral T2-relaxation time investigated with T2-mapping at multiple time points in a day demonstrate large individual variations.

PURPOSE The increasing interest of endplate and Modic changes as potential pain generators in low back pain (LBP), along with advancement of functional quantitative magnetic resonance imaging (MRI) techniques, makes it important to characterize the vertebral dynamic behavior in detail. This study aims to perform characterization of the dynamic behavior of the vertebral bodies (VB) by investigating the VB diurnal variation in T2-relaxation time in a cross-sectional asymptomatic group of individuals. METHODS T2-mapping of 30 VBs (L1-L5) in six healthy volunteers (mean age, 40 years; range, 29-65 years) was performed with a 1.

[Palytoxin poisoning related to salt water aquarium].

Palytoxin is a potent toxin found in zoanthid species, a popular decorative coral used in private aquaria. Inappropriate cleaning procedure may lead to palytoxin poisoning by dermal contact and inhalation of water aerosols, affecting several organ systems. This is a case report of three family members admitted to a hospital with symptoms compatible with palytoxin poisoning after cleaning an aquarium.