A Review of Energy-Based Device Interventions to Treat Keloid Scars.

Keloids are thickened raised scars that develop due to injury and grow beyond the boundaries of their original wound, mostly affecting individuals with skin of color. This review explores the use of energy-based devices to treat keloids, both using laser monotherapy and in combination with other drugs. Laser therapy alone has shown efficacy in treating keloids.

Cutaneous adverse effects associated with LAG-3 inhibitor use in cancer treatment: A systematic review.

Immunotherapy has become a mainstay of treatment for many cancers. Multiple immune checkpoint inhibitors have been used to treat malignancies, including anti-programed death-1 (PD1) and anti-cytotoxic T-lymphocyte-associated protein (anti-CTLA4). However, a significant percentage of patients develop resistance to these immunotherapy drugs.

Outcomes and adverse effects of ablative vs nonablative lasers for skin resurfacing: A systematic review of 1093 patients.

It is generally believed that ablative laser therapies result in prolonged healing and greater adverse events when compared with nonablative lasers for skin resurfacing. To evaluate the efficacy of ablative laser use for skin resurfacing and adverse events as a consequence of treatment in comparison to other modalities, a PRISMA-compliant systematic review (Systematic Review Registration Number: 204016) of twelve electronic databases was conducted for the terms "ablative laser" and "skin resurfacing" from March 2002 until July 2020. Studies included meta-analyses, randomized control trials, cohort studies, and case reports to facilitate evaluation of the data.

Concomitant use of isotretinoin and lasers with implications for future guidelines: An updated systematic review.

It is generally believed that intervention on skin while on isotretinoin or within 6 to 12 months after treatment can lead to prolonged healing and abnormal scarring. The objective of this systematic review is to evaluate the body of evidence on concomitant use of isotretinoin and lasers for adverse events as a consequence of treatment. A PRISMA-compliant systematic review (Systematic Review Registration Number: CRD42017056492) of 12 electronic databases was conducted for the terms "laser" and "isotretinoin" or associated brand names from inception until June 2020.

The use of lasers in the treatment of skin cancer: A review.

Background: In considering skin cancer, a number of factors-including effectiveness, simplicity of treatment, cost, and esthetic outcomes-are important to ensure patient's satisfaction. There are several existing interventions, such as electrodessication and curettage, excision, Mohs surgery, radiation therapy, cryotherapy, and topical/oral treatments. Laser therapy has emerged as a new promising alternative that should be explored.

High-fluence fractional treatment of photodamaged facial skin using a 2940 nm erbium:yttrium-aluminum-garnet laser.

Introduction: Fractional resurfacing with an Erbium:yttrium-aluminum-garnet (Er:YAG) 2940 nm laser is an increasingly popular option for the treatment of the signs of facial photoaging, which include wrinkles as well as pigmentation issues and unwanted textural changes. Fractional treatment has produced favorable clinical responses, but with less complications and shorter recovery times than traditional laser resurfacing. This study was conducted to evaluate a fractionated Er:YAG treatment regimen of 1-2 higher fluence sessions with a multiple-pass technique.

Laser scar revision: A review.

Surgery, burns, wounds, and inflammatory processes can lead to the development of a variety of different scars. Scars are categorized as hypertrophic, keloid, atrophic and acne scars. Different treatments are utilized for each scar type.

Reduction in thigh circumference and improvement in the appearance of cellulite with dual-wavelength, low-level laser energy and massage.

Objectives: This study evaluated the efficacy and safety of a low-level, dual-wavelength laser energy and massage device for improving the appearance of cellulite and reducing thigh circumference.

Methods: Subjects (n = 83) with mild to moderate cellulite enrolled in this IRB-approved, open-label, multicenter study. Their right or left thighs received eight treatments with a low-level, dual-wavelength laser and massage device.

Treatment of cutaneous lesions with a novel erbium-doped yttrium aluminum garnet laser with micron tips.

Background And Objective: The water content of epidermis below the stratum corneum is more than 70%. The 2,940-nm wavelength is at the peak of water absorption, making it an ideal wavelength for ablation of skin. The purpose of this study was to determine the effectiveness and safety of a novel erbium-doped yttrium aluminum garnet (Er:YAG) laser with micron tips in the removal of cutaneous lesions.

Derm diagnoses you can't afford to miss.

Management of hereditary angioedema should include fresh frozen plasma containing C1 inhibitor (C1-INH), whenever possible; if C1-INH-containing plasma is unavailable, fresh frozen plasma can be used instead. Do not give neomycin to patients with suspected cellulitis; the drug may promote antibiotic resistance in Staphylococcus aureus, a pathogen often associated with this condition. Whenever a patient presents with erythematous skin lesions and a recent history of receiving penicillin or a cephalosporin antibiotic, a sulfa derivative, or an anticonvulsant, the suspected medication should be stopped until Stevens-Johnson syndrome is ruled out.

Efficacy and safety of a 0.65 millisecond pulsed portable ND:YAG laser for hair removal.

Background And Objective: Based upon the thermal relaxation time of the hair follicle (10-50 ms), most lasers and light devices use relatively long pulse widths for hair removal. This study was conducted to evaluate a shorter pulsed, 0.65 ms Nd:YAG laser for hair removal.

Micro-fractional ablative skin resurfacing with two novel erbium laser systems.

Background And Objectives: Fractional ablation offers the potential benefits of full-surface ablative skin resurfacing while minimizing adverse effects. The purpose of this study was to evaluate the safety, damage profile, and efficacy of erbium fractional lasers.

Materials And Methods: Histology from animal and human skin as well as clinical evaluations were conducted with erbium YAG (2,940 nm) and erbium YSGG (2,790 nm) fractional lasers varying pulse width, microbeam (microb) energy, number of passes, and stacking of pulses.

Bilateral aberrant axillary breast tissue mimicking lipomas: report of a case and review of the literature.

A 31 year old Indian woman presented with bilateral axillary masses that became noticeable with the onset of puberty. The masses exhibited similar consistency to the adjacent normal breast tissue but lacked an associated nipple complex. The clinical impression was lipoma; however, mammography, ultrasonography and skin biopsy revealed ectopic breast tissue.

Comparison of the open technique with a new wound dressing, H2460, in the healing of an acute wound after laser skin resurfacing.

Background: Applying various dressings or leaving the treated area open are two techniques in use after laser skin resurfacing (LSR).

Objective: This study was conducted to compare healing of an acute wound using a new hydrocolloid dressing, H2460, with the open technique.

Methods: Immediately after LSR, one side was covered with the new hydrocolloid dressing H2460 and the other side was left open.

Erbium:YAG laser resurfacing using a novel portable device.

Laser resurfacing of facial rhytids has become a popular treatment for many patients who have wrinkles, photodamage, and acne scarring. Erbium:YAG laser resurfacing has emerged as one of the safer, more effective methods of facial rejuvenation and its increasing popularity has led to its widespread use for resurfacing. However, size and high initial and maintenance cost are among the problems with currently available laser devices.

Laser skin resurfacing with a novel portable erbium:YAG laser.

Background And Objective: The erbium:YAG laser is a popular modality for laser skin resurfacing (LSR). This study was performed to evaluate the safety and efficacy of a new portable Er:YAG laser in the treatment of photo-damaged skin.

Methods: Nine patients with skin types I-III were treated for rhytides, large pores, pigmented lesions, lentigines and photo-damage.

Comparison of two wound dressings after laser skin resurfacing.

Background: It has been reported that the final outcome of laser resurfacing still depends to a large degree on the efficiency of the post laser resurfacing wound care in promoting wound healing and preventing early and late complications.

Objective: The objective of this study was to evaluate and compare a new hydrocolloid dressing, H2460, with Flexzan(TM) for healing of an acute wound after laser skin resurfacing (LSR).

Methods: Ten volunteers received LSR of the peri-orbital area with an erbium:YAG laser.

Diode laser hair removal in patients undergoing isotretinoin therapy.

Background: It is generally believed that any intervention in skin while on isotretinoin or within 6 months after the treatment can lead to prolonged healing and scarring.

Objective: The objective was to evaluate the side effects of laser hair removal in patients undergoing isotretinoin treatment.

Methods: Seven female patients undergoing isotretinoin therapy for acne were treated with a diode laser with a wavelength of 810 nm, a contact-cooling device, and a variable pulse width of 50 to 1000 ms.

Erbium:YAG laser skin resurfacing: a Pakistani experience.

Background And Objectives: To evaluate the use of the erbium:YAG laser for resurfacing in type IV skin patients in Pakistan.

Study Design/materials And Methods: Ten patients with skin type IV underwent laser skin resurfacing with an erbium:YAG laser to treat wrinkles, acne/chickenpox scars and hyperpigmentation. An evaluation was done by the treating physician and a photographic evaluation and grading was done by a blinded observer.