IgD-λ multiple myeloma with excessive excretion of free light chains: a diagnostic trap in the identification of monoclonal gammopathies.

Immunoglobulin D multiple myeloma (IgD MM) is a rare entity of monoclonal gammopathies. We report the case of a IgD MM, associated with excessive excretion of lambda free light chains (FLL λ) diagnosed and managed at the University Hospital Mohammed VI of Marrakech among an adult hospitalized in the hematology department for bone pain and alteration of the general condition. Indeed, IgD MM is characterized by its clinical severity and poor prognosis.

[Estimation of reference ranges for full blood count (FBC) in Marrakech: preliminary study conducted at Center Hospital University Mohammad VI (CHU), Marrakech].

Introduction: The full blood count (FBC) is one of the most commonly requested and useful test in common medical practices. Abnormalities can indicate the presence of many disorders. A correct interpretation is then essential to guide the diagnosis.

[T-cell prolymphocytic leukemia revealed by spinal cord compression].

T-cell prolymphocytic leukemia is a lymphoid hematologic malignancy of T origin, mature, individualized well by the clinical, morphological, and immunophenotypic as well as cytogenetic aspects. We report the case of a 39-year-old man admitted in our department because of a spinal cord compression. The cerebrospinal fluid analysis had revealed an increased albuminemia level; MRI evoked a vertebral infiltration by a malignancy.

Contributions of biological tests and the 4 Ts score in the diagnosis of heparin induced thrombocytopenia.

Introduction: Heparin-induced thrombocytopenia (HIT) is an adverse drug reaction caused by antibodies to the heparin/platelet factor 4 (PF4) complexes. HIT diagnosis is challenging and depends on clinical presentation and laboratory tests. We investigated the interest of the combined use of 4 Ts score and the functional and immunological tests for the diagnosis of HIT.