Publications by authors named "Khalid Nafie"

Key Clinical Message: Castleman's Disease should be considered in the differential diagnosis of retroperitoneal masses, especially in equivocal cases. Clinician should not presume all cases of retroperitoneal masses as a malignancy.

Abstract: Castleman's Disease is a heterogeneous group of lymphoproliferative disorders, that can develop in lymph nodes or in extranodal sites.

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Hemangiomas are common lesions in medical practice, but those arising in the nasal cavity and/or paranasal sinuses are rare. Inverted papilloma is a rare benign tumor with a high incidence rate in both the nasal cavity and sinuses. The presence of both lesions in the same patient is even rarer.

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  • Pregnant women at high altitudes (around 2200 m) face challenges like hypoxia and a higher likelihood of early pregnancy disorders, with about 19% experiencing miscarriage.
  • A study analyzed data from 495 women diagnosed with early pregnancy disorders between 2018-2020, revealing that missed miscarriages were the most common type, particularly affecting women aged 35 and older.
  • The research indicates a higher prevalence of molar pregnancies than previously reported, highlighting the need for better monitoring and further studies comparing high-altitude populations with those at sea level.
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Background: Eosinophilic cystitis (EC) is a rare inflammatory urinary bladder disorder whose etiology, pathogenesis, and treatment are unknown. The work aims to evaluate the clinical manifestations, cystoscopic characteristics, pathological features, treatment, and clinical outcome of EC patients.

Materials And Methods: The clinical records and histopathology material of 22 patients diagnosed as EC during ten years were reviewed and analyzed for patient's age, sex, clinical data, cystoscopic features, biopsy procedures, treatment plan, follow-up, and prognosis.

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Background: Healthcare workers have a higher risk of acquiring coronavirus disease 2019 (COVID-19). The process of requesting pathological investigations is usually handled manually through paper-based forms. This study evaluated the potential for paper-based request forms to transmit severe acute respiratory virus coronavirus-2 (SARS-CoV-2) to laboratory staff in order to make recommendations for dealing with hospital paperwork in a post-COVID-19 world.

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  • Fallopian tubal molar pregnancy is rare, and it's usually diagnosed after surgery through histopathological examination rather than pre-operatively.
  • A case is presented involving a 35-year-old woman with an ectopic partial molar pregnancy in her right fallopian tube.
  • The initial clinical diagnosis was ectopic pregnancy, but the histopathology report later unveiled unexpected findings.
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Background: Routine histopathological examination (RHPE) of all gallbladder specimens is required to detect the presence of gallbladder carcinoma (GBC) or any other pathology. The work aims to study the incidence and the clinical significance of detecting unusual gallbladder findings upon the RHPE of the referred cholecystectomy specimens to a histopathology laboratory section at a referral hospital in Saudi Arabia during one year period.

Materials And Methods: From May 2019 to May 2020, all histopathology reports of 444 consecutive gallbladder specimens after elective and emergency cholecystectomies were retrospectively analyzed and divided into two groups; usual findings and unusual findings which were reviewed blindly by two other pathology consultants.

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  • This study investigates how common Enterobius vermicularis infestation is in patients who have undergone appendectomy and examines its connection to acute appendicitis.
  • Out of 1150 appendectomy cases reviewed over three years, only 31 (2.7%) were found to have E. v infestation; most of these cases involved children, and many presented no additional appendiceal issues.
  • The study concludes that while E. v infestation can be found incidentally in appendectomy specimens, there is no established relationship between E. v and acute appendicitis, signaling a need for further research and caution during surgical procedures to avoid unnecessary complications.
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  • Eccrine poroma is a benign tumor that usually occurs on the hands and feet but is rarely found in the gluteal area, marking the first reported case of such a recurrence.
  • A 62-year-old woman developed a recurrent eccrine poroma in her buttocks after initial surgical removal, following mild trauma, which led to an abscess.
  • The rarity of eccrine poromas in unusual locations highlights the need for careful monitoring and treatment to differentiate them from potentially more serious conditions, emphasizing the importance of complete resection and follow-up.
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