Overcrowding and possible solutions for a busy paediatric emergency department.

Objective: To quantify the extent of emergency department overcrowding in a tertiary care hospital and to identify possible solutions.

Methods: This retrospective study was conducted at the National Institute of Child Health, Karachi, and comprised data of all patients presenting to the emergency department from November 2014 to January 2015. Data was collected through the health management information system which generates daily report of patients.

Study of PKRBD in HCV genotype 3a infected patients in response to interferon therapy in Pakistani population.

Background: Hepatitis C virus (HCV) is a major cause of liver cirrhosis and hepatocellular carcinoma and infects about 3% world population. Response to interferon therapy depends upon the genotype of the virus and factors associated with the host. Despite a good response to interferon therapy, a considerable number of genotype 3a infected patients remains unalleviated.

1-(5a,5b,8,8,11a,13b-Hexamethyl-eicosa-hydro-1H-cyclo-penta-[a]chrysen-3-yl)-1-ethanone.

The title compound, C(29)H(48)O, is a triterpenoid isolated from Adiantum incisum forssk. In the crystal structure, the asymmetric unit contains two independent mol-ecules which are not significantly different. Each mol-ecule contains four six-membered rings, all adopting chair conformations, and a five-membered ring in an envelope conformation.