Publications by authors named "Khalid Mahmood Khan Nafees"

Background: There is conflicting evidence on association between quick sequential organ failure assessment (qSOFA) and sepsis mortality in ICU patients. The primary aim of this study was to determine the association between qSOFA and 28-day mortality in ICU patients admitted for sepsis. Association of qSOFA with early (3-day), medium (28-day), late (90-day) mortality was assessed in low and lower middle income (LLMIC), upper middle income (UMIC) and high income (HIC) countries/regions.

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  • The study examined current mechanical ventilation practices in Asian intensive care units, specifically focusing on tidal volume, plateau pressure, and PEEP in patients.
  • Data from 1408 patients were analyzed, highlighting that while low tidal volume was utilized in patients with ARDS, a large proportion of those without ARDS received intermediate tidal volumes, with adequate plateau pressure noted in most cases.
  • The research found that factors like income classification, patient age, severity of illness, and certain clinical measures significantly influenced mortality rates, which escalated with higher predictive scores for mortality.
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  • A study examined sepsis prevalence and treatment practices in adult ICUs across 22 Asian countries with varying income levels, revealing an overall sepsis prevalence of 22.4%.
  • The study found that patients in low-income and lower-middle-income regions tended to be younger and less severely ill but experienced higher hospital mortality rates (32.6%) compared to those in high-income countries.
  • Compliance with sepsis treatment protocols (the sepsis bundle) was low, particularly the timely administration of antibiotics, which when delayed beyond 3 hours, significantly increased the risk of mortality.
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Background: Asia has more critically ill people than any other part of our planet. The aim of this article is to review the development of critical care as a specialty, critical care societies and education and research, the epidemiology of critical illness as well as epidemics and pandemics, accessibility and cost and quality of critical care, culture and end-of-life care, and future directions for critical care in Asia.

Main Body: Although the first Asian intensive care units (ICUs) surfaced in the 1960s and the 1970s and specialisation started in the 1990s, multiple challenges still exist, including the lack of intensivists, critical care nurses, and respiratory therapists in many countries.

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Objective: To assess the number of adult critical care beds in Asian countries and regions in relation to population size.

Design: Cross-sectional observational study.

Setting: Twenty-three Asian countries and regions, covering 92.

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