Synthetic Hybrid-Scale Fiber Matrix for the Treatment of Complex Lower-Extremity Wounds.

Background: Chronic, nonhealing wounds are a growing health-care problem in the United States, affecting more than 6.5 million patients annually and costing the health-care system over $25 billion. Chronic wounds, including diabetic foot ulcers (DFUs) and venous leg ulcers (VLUs), are often difficult to treat, and patients commonly fail to heal even with the most advanced therapies.

Awareness of food allergies: a survey of pediatricians in Kuwait.

Background: Early diagnosis of food allergies (FA) is important for a favorable prognosis. This study aimed to determine the level of awareness of FA among pediatricians in Kuwait.

Method: A 43-item self-administered questionnaire was designed and distributed to pediatricians working at 4 government hospitals in Kuwait.

Complications in paediatric liver transplant from Kuwait when transplanted abroad.

Background And Study Aims: Since the introduction of liver transplantation (LTx) in children suffering from liver failure in 1963, many centres around the world have offered this service to children that have no other alternative. The aim of this retrospective study is to analyse the results of paediatric liver transplant in Kuwait over the last decade.

Patients And Methods: A retrospective chart review was done involving paediatric patients during the time period of 1995-2004.

Loss of interleukin-10 signaling and infantile inflammatory bowel disease: implications for diagnosis and therapy.

Background & Aims: Homozygous loss of function mutations in interleukin-10 (IL10) and interleukin-10 receptors (IL10R) cause severe infantile (very early onset) inflammatory bowel disease (IBD). Allogeneic hematopoietic stem cell transplantation (HSCT) was reported to induce sustained remission in 1 patient with IL-10R deficiency. We investigated heterogeneity among patients with very early onset IBD, its mechanisms, and the use of allogeneic HSCT to treat this disorder.

Performance status and deaths among children registered in Kuwait National Primary ImmunoDeficiency Disorders Registry.

Children with primary immunodeficiency disorders (PIDD) have an increased risk of suffering from physical, social, and psychological problems. The aim of this study was to evaluate the performance status and mortality of children with PIDD in Kuwait and to determine the variables and co-morbidities that may affect their performance and risk of death. The data for the children were obtained from Kuwait National Primary Immunodeficiency Disorders Registry describes the patients' characteristics, comorbidities and their treatment regimens.

Primary immunodeficiency disorders: survey of pediatricians in Kuwait.

Introduction: Early diagnosis of primary immunodeficiency disorders (PID) is critical so life saving interventions can be implemented to avoid significant morbidity and mortality. Unfortunately, they are frequently misdiagnosed, which results into significant delay in diagnosis. This study aimed to determine the knowledge and practice of pediatricians in Kuwait about PID.

Epidemiology and outcome of severe hepatitis A infection in children in Kuwait.

Objective: To describe the epidemiology, clinical features and outcome of hepatitis A virus (HAV) infection in children in Kuwait.

Subjects And Method: The medical records of 350 patients (age 0-16 years) admitted to the Infectious Diseases Hospital, Kuwait, between January 2000 and December 2002, with hepatitis A infection were reviewed.

Results: The mean age was 8.