Publications by authors named "Khalid AlRumaihi"
Article Synopsis
- Robotic assisted partial nephrectomy is the preferred treatment for small kidney tumors, but it can lead to rare complications like ureteric stricture, affecting patient wellbeing.
- Surgical options for severe stricture may not be suitable for high-risk patients, who may require alternatives like a ureteric double J stent or nephrostomy tube.
- A case study showed that when conventional surgery isn't possible due to tumor proximity, using a metallic ureteral stent (Memokath) provides better durability and improves the quality of life compared to double stents for managing ureteric strictures.
Background: Studies exploring the effect of COVID-19 on male reproductive system suggest a detrimental association, however with conflicting results. The aim of this study was to assess the association between COVID-19 infection and male reproductive potential including hormone profiles and semen parameters.
Methods: This prospective cohort study included 48 patients with confirmed COVID-19 infection.
Article Synopsis
- Benign prostatic hyperplasia (BPH) is the leading cause of urinary retention in men, and while traditional surgery (TURP) is effective, it has significant risks, prompting interest in less invasive options like the Rezum system.
- A systematic review of studies using Rezum found it to be effective in treating urinary retention from BPH, with an 85% success rate in patients who had previously relied on catheters.
- Rezum therapy showed a low complication rate (3.8 to 4.3%), with only mild and self-limited issues, making it a safe alternative to more invasive surgical options.
Introduction: Chronic pelvic pain syndrome (CPPS) is a frequent urological diagnosis that affects men's quality of life. Extracorporeal shockwave therapy (ESWT) is a recent treatment option for patients with CPPS. We evaluated ESWT's short and long - term efficacy in managing CPPS.
View Article and Find Full Text PDFBackground: To date, no previous research assessed the bibliometrics of men's sexual and reproductive healthcare (SRHC) across Arab countries. This study appraised the current standing of men's SRHC research in the MENA (Middle East and North Africa) region.
Methods: We performed a bibliometric analysis to assess qualitatively and quantitatively the peer-reviewed articles published from Arab countries from inception to 2022.
Background: No study appraised the knowledge gaps and factors impacting men's sexual and reproductive health (SRH) in MENA (Middle East and North Africa). The current scoping review undertook this task.
Methods: We searched PubMed and Web of Science (WoS) electronic databases for original articles on men's SRH published from MENA.
Objective: We appraised the reporting quality of abstracts of systematic reviews/meta-analyses (SR/MAs) published in one urology journal and explored associations between abstract characteristics and completeness of reporting.
Methods: The Arab Journal of Urology (AJU) was searched for SR/MAs published between January 2011 and 31 May 2022. SR/MAs with structured abstract and quantitative synthesis were eligible.
The use of cryoablation in the management of small renal masses is widely acceptable. Although rare but ureteral injury during the procedure with subsequent stricture formation can result in devastating effects on renal function. On the other hand, the management of such strictures requires reconstructive surgery as gold standard.
View Article and Find Full Text PDFDiabetes mellitus is associated with increased risk of erectile dysfunction. Penile prosthesis implantation is an efficient therapeutic option for erectile dysfunction, but not without risk, as infection remains a prominent concern. This study investigates diabetes mellitus as a risk factor for penile prosthesis implantation infection and the relationship between haemoglobinA1c levels and infection rates.
View Article and Find Full Text PDFBackground: User interfaces play a vital role in the planning and execution of an interventional procedure. The objective of this study is to investigate the effect of using different user interfaces for planning transrectal robot-assisted MR-guided prostate biopsy (MRgPBx) in an augmented reality (AR) environment.
Method: End-user studies were conducted by simulating an MRgPBx system with end- and side-firing modes.
Non-alcoholic fatty liver disease (NAFLD) is associated with cardiovascular disease (CVD) and both are prevalent in men with testosterone deficiency. Long-term effects of testosterone therapy (TTh) on NAFLD are not well studied. This observational, prospective, cumulative registry study assesses long-term effects of testosterone undecanoate (TU) on hepatic physiology and function in 505 hypogonadal men (T levels ≤350 ng/dL).
View Article and Find Full Text PDFBackground: This study presents user evaluation studies to assess the effect of information rendered by an interventional planning software on the operator's ability to plan transrectal magnetic resonance (MR)-guided prostate biopsies using actuated robotic manipulators.
Methods: An intervention planning software was developed based on the clinical workflow followed for MR-guided transrectal prostate biopsies. The software was designed to interface with a generic virtual manipulator and simulate an intervention environment using 2D and 3D scenes.
Article Synopsis
- The study evaluates how multi-parametric MRI can help distinguish benign testicular stromal tumors (STs) from malignant testicular neoplasms (MTNs).
- Results showed that MTNs were significantly larger and displayed different MRI characteristics compared to STs, such as T2-weighted signal intensity and enhancement patterns.
- A model using MRI features like T2-weighted imaging, diffusion-weighted imaging, and dynamic contrast enhancement provided the best diagnostic accuracy for identifying these tumors.
Prostate cancer (PC) castration resistance has been linked to the differentiation of PC luminal cells into hormone-refractory neuroendocrine (NE) cells. However, the molecular mechanisms controlling the emergence of lethal NE prostate cancer (NEPC) remain unclear. The present study aimed to investigate the mechanisms underlying the transition from prostate adenocarcinoma to NEPC.
View Article and Find Full Text PDFArticle Synopsis
- The use of α-blockers for medical expulsive therapy (MET) in treating ureteric stones has been debated and examined in various randomized controlled trials.
- A systematic review and meta-analysis showed that α-blockers are effective specifically for stones larger than 5 mm and those located in the distal ureter, as they improve stone expulsion rates.
- Although the treatment is beneficial, it's important to note that there is a minor increase in the risk of side effects, though they are mostly nonsignificant.
Background: Prostate cancer (PCa) is a complex disorder resulting from the combined effects of multiple environmental and genetic factors. Small non-coding RNAs (sRNAs), particularly microRNAs (miRNAs), regulate several cellular processes and have an important role in many human malignancies including PCa. We assessed the sRNA profiles associated with PCa in Arabs, a population that has rarely been studied.
View Article and Find Full Text PDFPurpose: To determine the effect of Ramadan intermittent fasting on erectile function (EF), sexual desire and serum hormone levels.
Materials And Methods: Eligible male participants completed the two domains of International Index of Erectile Function (IIEF) questionnaire for EF and sexual desire. They also provided information on any known disease, treatment taking, smoking habits and frequency of sexual intercourse.
Background: Large databases focused on genetic susceptibility to prostate cancer have been accumulated from population studies of different ancestries, including Europeans and African-Americans. Arab populations, however, have been only rarely studied.
Methods: Using Affymetrix Genome-Wide Human SNP Array 6, we conducted a genome-wide association study (GWAS) in which 534,781 single nucleotide polymorphisms (SNPs) were genotyped in 221 Tunisians (90 prostate cancer patients and 131 age-matched healthy controls).
Background: Photoselective vaporization (PVP) with the GreenLight HPS 120-W laser (GLL) was recently introduced for treatment of benign prostatic hyperplasia (BPH).
Objective: To compare results of GLL PVP and transurethral resection of the prostate (TURP) for treatment of BPH.
Design, Setting, And Participants: A total of 120 patients with BPH were randomly assigned to two equal groups: TURP or PVP.