Anticoagulation activity of sulfated carboxymethyl cellulose/ leaf powder-based bio-composite.

Polymeric bio-composites synthesized a green approach using natural herbs have fascinating anticoagulant activity due to their eco-friendly and non-toxic behavior towards various physical and chemical actions. Herein, we introduce a simple and eco-friendly approach for the fabrication of a new hybrid type of bio-composite based on sulfated carboxymethyl cellulose (S-CMC) and leaf powder (S-CMC/NLP). First, a non-toxic sulfating agent called N(SONa) was used to modify carboxymethyl cellulose into S-CMC.

Carboxymethylcellulose encapsulated fingolimod, siRNA@ZnO hybrid nanocomposite as a new anti-Alzheimer's material.

Alzheimer's disease (AD) is a fatal neurological disorder that causes cognitive and memory function to deteriorate. A critical pathogenic event that speeds up the development of AD is the interaction between dysfunctional microglia and amyloid-β (Aβ). We have developed a hybrid nanocomposite material to treat AD by normalizing the dysfunctional microglia.

Ionic Organic Network-based C3-symmetric@Triazine core as a selective Hg sensor.

The C3-symmetry ionic polymer PPyTri has been designed with multi-walled carbon nanotubes (MWCNTs) or graphene nanoplatelets (GNPs) and studied as an ultrasensitive electrochemical sensor for trace Hg(II) detection. The synthesis approach incorporated attaching three pyridinium cationic components with chloride anions to the triazine core. The precursors, BPy, were synthesized using a condensation process involving 4-pyridine carboxaldehyde and focused nicotinic hydrazide.

Development of an efficient electrochemical sensing platform based on ter-poly(luminol--anisidine--toluidine)/ZnO/GNPs nanocomposites for the detection of antimony (Sb) ions.

A poly(luminol--anisidine--toluidine) terpolymer was synthesized, characterized, and modified with GNPs and ZnO NPs. The nanocomposites were then examined for their electroactivity and potential use as cationic electrochemical sensors for detecting Sb ions in phosphate buffer on the surface of a glassy carbon electrode (GCE). Among the different compositions and the terpolymer, the GCE adapted with the PLAT/ZnO/GNPs-5% nanocomposite displayed the highest current response.

C3-Symmetric ligands in drug design: An overview of the challenges and opportunities ahead.

C3-symmetry is a type of star-shaped molecule consisting of a central core and three symmetrically attached chains. These molecules are used in drug discovery due to their unique three-fold rotational symmetry, which allows for specific binding interactions and improved molecular recognition. In this text, we provide an overview of synthetic approaches with C3-symmetry as a pharmaceutical tool: progress, challenges, and opportunities.

Sensitive Cr sensor based on novel poly(luminol--1,8-diaminonaphthalene)/CeO/MWCNTs nanocomposites.

In this study, poly(luminol--1,8-diaminonaphthalene) (PLim-DAN) was synthesized and subsequently modified with MWCNTs and CeO NPs. The synthesized nanocomposites were analyzed using IR, SEM, TEM, and XRD. Furthermore, a comprehensive set of thermal behavior measurements were taken using TGA/DTG analysis.

Tropical soil remediation from pyrene: Release the power of natural iron content in soil for the efficient oxidant's activation.

Natural soil minerals often contain numerous impurities, resulting in comparatively lower catalytic activity. Tropical soils are viewed as poor from soil organic matter, cations, and anions, which are considered the main impurities in the soil that are restricted to utilizing natural minerals as a catalyst. In this regard, the dissolved iron and hematite crystals that presented naturally in tropical soil were evaluated to activate oxidants and degrade pyrene.

New sorbent-based hydrophobic alginic acid derivatives for fat removal in multi-pesticide residues: analysis of a fatty food sample.

Hydrophobic alginic acid derivatives were synthesized with various aliphatic hydrocarbon chains for fat removal in an analysis of multi-pesticide residues in a fatty food sample. First, alginic acid was chemically modified using eco-friendly ultrasound-assisted esterification with different alcohols, namely, hydrophobic alginic acid-methanol (HAA-C1), hydrophobic alginic acid-butanol (HAA-C4), and hydrophobic alginic acid-octadecanol (HAA-C18). The degree of esterification (DE) was determined by titration, and the results ranged from 57.

One-pot multicomponent polymerization towards heterocyclic polymers: a mini review.

Multicomponent polymerization (MCP) is an innovative field related to polymer-based chemistry that offers numerous advantages derived from multicomponent reactions (MCRs). One of the key advantages of MCP is its ability to achieve high efficiency. Additionally, MCP offers other advantages, including operational simplicity, mild reaction conditions, and atom economy.

Hydrophobic carboxymethyl cellulose as a clean-up sorbent in the determination of nitrofuran metabolites in animal-fat samples.

Hydrophobic carboxymethyl cellulose (CMC) biopolymers were fabricated for the removal of fat from food sample matrices. The hydrophobic CMCs were synthesised the esterification of CMC with three alcohols with carbon chains of different lengths, methanol, butanol, and octadecanol, in the presence of sulfuric acid. The structure of the three synthesised hydrophobic CMCs was verified using FT-IR, and the physicochemical properties were investigated by TGA, SEM, and X-ray.

Modified TPP-MoS QD Blend as a Bio-Functional Model for Normalizing Microglial Dysfunction in Alzheimer's Disease.

Alzheimer's disease (AD) is the most prevalent neurodegenerative disease of old age. Accumulation of β-amyloid peptide (Aβ) and mitochondrial dysfunction results in chronic microglial activation, which enhances neuroinflammation and promotes neurodegeneration. Microglia are resident macrophages of the brain and spinal cord which play an important role in maintaining brain homeostasis through a variety of phenotypes, including the pro-inflammatory phenotype and anti-inflammatory phenotypes.

Correction: Hybridized sulfated-carboxymethyl cellulose/MWNT nanocomposite as highly selective electrochemical probe for trace detection of arsenic in real environmental samples.

[This corrects the article DOI: 10.1039/D3RA03808D.].

Branched Fluorenylidene Derivatives with Low Ionization Potentials as Hole-Transporting Materials for Perovskite Solar Cells.

A group of small-molecule hole-transporting materials (HTMs) that are based on fluorenylidene fragments were synthesized and tested in perovskite solar cells (PSCs). The investigated compounds were synthesized by a facile two-step synthesis, and their properties were measured using thermoanalytical, optoelectronic, and photovoltaic methods. The champion PSC device that was doped with lithium bis(trifluoromethanesulfonyl)imide (LiTFSI) reached a power conversion efficiency of 22.

Green synthesis of heterocyclic alkenes using MCM 41 supported perchloric acid catalytic system: characterization and DFT studies.

Context: In this work, a series of heterocyclic alkenes were prepared by the reaction of 2-hydroxy-1-naphthaldehyde with various heterocyclic active methylene compounds via Knoevenagel condensation reaction using mesoporous silica, MCM 41, supported perchloric acid as an efficient green catalytic system under solvent-free conditions. A comparative study of the conventional method vs the green method was also reported with the same raw materials. H NMR, C NMR, IR, and mass spectroscopic techniques were used for the characterization of synthesized compounds.

Recent advances in bio-based polybenzoxazines as an interesting adhesive coating.

Polybenzoxazine (PBz) is an excellent and highly intriguing resin for various sophisticated uses. Benzoxazines have piqued the curiosity of academics worldwide because of their peculiar properties. Nonetheless, most benzoxazine resin manufacturing and processing methods, notably bisphenol A-based benzoxazine, rely on petroleum resources.

Hybridized sulfated-carboxymethyl cellulose/MWNT nanocomposite as highly selective electrochemical probe for trace detection of arsenic in real environmental samples.

A highly selective and ultra-sensitive electrochemical sensing probe was proposed by combining sulfated-carboxymethyl cellulose (CMC-S) and a functionalized-multiwalled carbon nanotube (f-MWNT) nano-composite with high conductivity and durability. The CMC-S/MWNT nanocomposite was impregnated on a glassy carbon electrode (GCE) to construct the non-enzymatic and mediator-free electrochemical sensing probe for trace detection of As(iii) ions. The fabricated CMC-S/MWNT nanocomposite was characterized by FTIR, SEM, TEM, and XPS.

Corrosion inhibition of mild steel in hydrochloric acid solution by the expired Ampicillin drug.

This study examines the utilization of the expired drug, namely ampicillin, as a mild steel corrosion inhibitor in an acidic environment. The inhibitor was evaluated using weight loss and electrochemical measurement accompanied with surface analytical techniques. The drug showed a potential inhibitory efficiency of > 95% at 55 °C.

An overview of the synthetic strategies of 3-symmetric polymeric materials containing benzene and triazine cores and their biomedical applications.

3-symmetric star-shaped materials are an emerging category of porous organic polymers with distinctive properties such as permanent porosity, good thermal and chemical stability, high surface area, and appropriate functionalization that promote outstanding potential in various applications. This review is mostly about constructing benzene or -triazine rings as the center of 3-symmetric molecules and using side-arm reactions to add functions to these molecules. Over and above this, the performance of various polymerization processes has been additionally investigated in detail, including the trimerization of alkynes or aromatic nitriles, polycondensation of monomers with specific functional groups, and cross-coupling building blocks with benzene or triazine cores.

Signal Transducer and Activator of Transcription 6 Changes and Protein Frustration by Single Amino Acid Substitutions: Implications for Cancer Progression.

Signal transducer and activator of transcription 6 (STAT6) is a multifunctional protein that plays critical functions in cell proliferation, apoptosis, differentiation, and angiogenesis. Mutations in STAT6 may contribute to the development of certain complex diseases such as cancer. This study examined single amino acid substitutions in STAT6 to pinpoint deleterious variants and their related structural and functional impairments.

Enhancing the Photovoltaic Properties via Incorporation of Selenophene Units in Organic Chromophores with A-π-A-π-A Configuration: A DFT-Based Exploration.

Currently, polymer organic solar cells (POSCs) are widely utilized due to their significant application, such as low-cost power conversion efficiencies (PCEs). Therefore, we designed a series of photovoltaic materials ( and ) by the incorporation of selenophene units ( = 1-7) as π-spacers by considering the importance of POSCs. Density functional theory (DFT) calculations were accomplished at MPW1PW91/6-311G (d, p) functional to explore the impact of additional selenophene units on the photovoltaic behavior of the above-mentioned compounds.

Exploiting poly(safranine) and poly(luminol) for sensing applications. A mini review.

Sensor applications have captivated numerous scientists in the electroactivity field lately. Between toxic target analytes and biomolecules, many articles investigated the function of the obtained products in sensing utilization and the ability of applying the gained sensor in real sample tests. Safranine and luminol have a unique polymeric constructor combined with different nanomaterials and have been explored as sensors for different analytes through electrochemical and chemical techniques.

An investigation on the adsorption and removal performance of a carboxymethylcellulose-based 4-aminophenazone@MWCNT nanocomposite against crystal violet and brilliant green dyes.

The multistep chemical modification of carboxymethylcellulose (CMC) in the presence of 4-aminophenazone (A-PH) and multiwall carbon nanotubes (MWCNTs) has been successfully conducted. The environmental performance of this material has been thoroughly investigated. Crystal violet (CV) and brilliant green (BG) were eliminated by utilising a new hybrid nanocomposite material (A-PH-CMC/MWCNTs) from a simulated textile wastewater solution.

Synthesis and Characterization of Eco-Friendly Bio-Composite from Fenugreek as a Natural Resource.

The present study show the usability of starch (tamarind) based-bio-composite film reinforced by fenugreek by various percentages to replace the traditional petrochemical plastics. The prepared bio-composite films were systematically characterized using the universal testing machine (UTM), soil degradation, scanning electron microscope (SEM), X-ray diffraction (XRD), thermogravimetric analyzer (TGA), and antibacterial tests. The experiments showed that a lower percentage of fenugreek improves biodegradation and mechanical strength.