Publications by authors named "Khaled Mokaddem"
Article Synopsis
- A study examined the relationship between serum uric acid (UA) levels and disease activity in rheumatoid arthritis (RA) patients, finding that 15% of patients had high UA levels.
- The research included 1,054 RA patients from the Kuwait Registry, revealing that those with higher UA levels had a lower disease activity score (DAS28) and similar health assessment questionnaire (HAQ) scores regardless of drug treatment.
- The findings suggest a complex link where higher UA is associated with reduced RA activity, indicating the need for further investigation into this relationship.
Background: Rheumatoid arthritis (RA) is a chronic, autoimmune disease that mostly affects the synovial joints. It has been hypothesized that dietary and other environmental and lifestyle factors contribute to the development of RA and its severity.
Objective: The present study aims to measure the effect of the Mediterranean diet (MedDiet) on the disease activity scores (DAS28) among patients with RA.
Objective: Biologics are indicated in rheumatoid arthritis (RA) in case of persistent high disease activity despite conventional disease-modifying anti-rheumatic drugs (cDMARDs) or patients with contraindications to cDMARDs or poor prognostic factors. The purpose of this study was to compare the prescription rates of biologics in Kuwaiti and non-Kuwaiti patients and to assess whether this had an impact on disease activity and quality of life in RA patients.
Methods: Data were extracted from the Kuwait Registry for Rheumatic Diseases.
Article Synopsis
- The study evaluated 952 adult rheumatoid arthritis (RA) patients in Kuwait, finding that only 2.3% had rheumatoid nodules (RN).
- It showed that while demographic factors like age and sex were similar, patients with RN were more likely to be obese and reported higher levels of pain and joint deformities.
- Despite these differences, both groups exhibited low disease activity, but RN patients received more biologic therapy.