Feasibility of Ultrasound-Guided Lumbar Transforaminal Epidural Steroid Injections for Management of Lumbar Radicular Back Pain.

Background: Whereas traditional image guidance for placement of transforaminal epidural steroid injections (TFESI) has been fluoroscopy, it has disadvantages including inability to identify soft tissue, radiation exposure, and contrast administration need. Several studies found that ultrasonography is reliable in localizing lumbar nerve root. Few have investigated the feasibility of performing ultrasound guided TFESI in the lumbar spine.

Experimental and theoretical investigations of Erbium complex: DNA/BSA interaction, anticancer and antibacterial studies.

To assess the biological potential of an Er complex that contains a 2,2'-bipyridine ligand, various techniques such as multispectral and molecular modeling procedures were utilized to examine its DNA-binding ability, BSA binding affinity, antimicrobial effects, and anticancer properties. By analyzing fluorescent information and employing the vant' Hoff equation, important parameters such as the innate docking coefficient (K), Stern-Volmer coefficient (K), and thermodynamic properties including modifications in liberated energy (ΔG°), enthalpy (∆H°), and entropy (∆S°) were determined. The trial findings suggest that the compound can bind to DNA, primarily through groove binding.