Speech parameters may include perturbation measurements, spectral and cepstral modeling, and pathological effects of some diseases, like influenza, that affect the vocal tract. The verification task is a very good process to discriminate between different types of voice disorder. This study investigated the modeling of influenza's pathological effects on the speech signals of the Arabic vowels "A" and "O.
View Article and Find Full Text PDFIn this paper, we investigated the modeling of the pathological features of the influenza disease on the human speech. The presented work is novel research based on a real database and a new combination of previously used methods, discrete wavelet transform (DWT) and linear prediction coding (LPC). Three verification system experiments, Normal/Influenza, Smokers/Influenza, and Normal/Smokers, were studied.
View Article and Find Full Text PDFIEEE J Biomed Health Inform
November 2015
This paper evaluates the accuracy of different characterization methods for the automatic detection of multiple speech disorders. The speech impairments considered include dysphonia in people with Parkinson's disease (PD), dysphonia diagnosed in patients with different laryngeal pathologies (LP), and hypernasality in children with cleft lip and palate (CLP). Four different methods are applied to analyze the voice signals including noise content measures, spectral-cepstral modeling, nonlinear features, and measurements to quantify the stability of the fundamental frequency.
View Article and Find Full Text PDFPDZ domains have been identified as part of an array of signaling proteins that are often unrelated, except for the well-conserved structural PDZ domain they contain. These domains have been linked to many disease processes including common Avian influenza, as well as very rare conditions such as Fraser and Usher syndromes. Historically, based on the interactions and the nature of bonds they form, PDZ domains have most often been classified into one of three classes (class I, class II and others - class III), that is directly dependent on their binding partner.
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