New method for estimating arterial pulse wave velocity at single site.

The clinical importance of measuring local pulse wave velocity (PWV), has encouraged researchers to develop several local methods to estimate it. In this work, we proposed a new method, the sum-of-squares method [Formula: see text], that allows the estimations of PWV by using simultaneous measurements of blood pressure (P) and arterial diameter (D) at single-location. Pulse waveforms generated by: (1) two-dimensional (2D) fluid-structure interaction simulation (FSI) in a compliant tube, (2) one-dimensional (1D) model of 55 larger human systemic arteries and (3) experimental data were used to validate the new formula and evaluate several classical methods.

A new formula for predicting the position of severe arterial stenosis.

Noninvasive location of an occlusion or a severe stenosis in the arterial system is of a great interest for surgical interventions. Here, we present a new method to determine the location of arterial 99% stenosis in the arterial (sub) system. The method requires a measurement of propagation constant and the instantaneous flow rate or velocity at two sites of an arterial tree.