Hyperbaric oxygen in the treatment of calciphylaxis: A case series and literature review.

Aims: Calcific uraemic arteriolopathy (CUA) or calciphylaxis is most commonly seen in end-stage renal disease and is associated with significant morbidity and mortality. The aim of this study was to determine whether hyperbaric oxygen therapy (HBOT) is effective in healing calciphylaxis lesions and to determine if there are any patient factors that can predict wound healing and patient survival.

Methods: We identified by retrospective review all cases of CUA referred to our institution for treatment with HBOT.