GRADE-ADOLOPMENT of clinical practice guideline for postmenopausal osteoporosis management-a Pakistani context.

Unlabelled: Due to its high prevalence, we aimed to create postmenopausal osteoporosis clinical practice guideline via GRADE-ADOLOPMENT for Pakistan. We recommend a higher dose (2000-4000 IU) of vitamin D for osteoporotic patients who are old, have malabsorption, or are obese. The guideline will help standardize care provision and improve health care outcomes for osteoporosis.

COVID-19 related fears and adherence to infection control protocol amongst immunocompromised transplant recipients: A case study.

Background & Objective: Transplant recipients are at a high risk of critical COVID-19 illness due to chronic immunosuppression and their underlying medical condition. Our objective was to study the COVID-19 related fears and adherence to infection control measures in solid organ transplant recipients during COVID-19 pandemic.

Methods: A descriptive study was conducted during the first wave of COVID-19 pandemic (April- August 2020) in Punjab, Pakistan, as a part of province wide COVID-19 awareness drive 754 recipients registered at Punjab Human Organ Transplantation Authority (P-HOTA) for solid organ transplant were contacted telephonically and administered a self-constructed questionnaire.

Association of metabolic factors with dengue viral infection on admission triage which predict its clinical course during Lahore dengue epidemic.

Objective: The study was done to identify metabolic factors which were associated with an increased risk of dengue haemorrhagic fever in clinically diagnosed patients of dengue viral infection.

Methods: 563 patients with dengue viral infection that presented to 3 tertiary care hospitals of Lahore were included in this study, out of which approximately half of the patients were diagnosed as dengue haemorrhagic fever.

Results: A total of 563 patients with 263(46.

Diabetes and pancreatic cancer.

Research suggests a possible link between type 2 diabetes and several malignancies. Animal models have shown that hyperinsulinemic state underlying diabetes promotes tumor formation through stimulation of insulin-IGF-1 pathway; a possible role of inflammation is also proposed. One such link which has been under considerable study for years is that between diabetes and pancreatic cancer.