[The analysis of age dynamics of causes of mortality of population of elderly age groups as reserve of maintaining population of older able-bodied age].

The article analyzes age dynamics of initial causes of death according to records in medical death certificates of population of older age groups. Materials and methods. The records of causes of death of 34.

[The comparative analysis of health care systems based on rating definition].

The comparative analysis of effectiveness and efficiency of health care systems functioning causes a number of difficulties due to different indicators applied in countries as assessment tools, different data collection mechanisms and differences in nature and dimension of determining indicators. To ensure comparability of absolute values of various indicators and possibility to compare activities of single medical organizations and effectiveness of health care system of both various Subjects of the Russian Federation and health care system as a whole, it is possible to apply different rating techniques. The article presents comprehensive comparative analysis of activities of health care systems based on construction of rating using integral indicators of public health: indicators of key functioning of health systems (financial support and infrastructure development), total mortality from non-communicable diseases, probability of dying at the age of 30 to 70 years from any of cardiovascular diseases, cancer, diabetes or chronic respiratory diseases, universal health coverage index, life expectancy (at birth and at the age of 60).

[The personnel maintenance of primary health care physicians in condition of challenges from menaces to population health].

In condition of challenges from menaces to health due to COVID-19 the role of primary health care physicians increases that requires development of management decisions at the regional level. The purpose of the study. On the basis of analysis of medical demographic indicators and data concerning provision of primary health care personnel in the Russian Federation, proposals were made related to reforming of primary health care system in conditions of implementation of general medical practice with purpose to counteract menaces to population health.

[The comparative analysis of health care systems].

Within the framework of the national development goal of the Russian Federation "preservation of population, health and well-being of people" the target indicator "the increase of life expectancy up to 78 years" is to be achieved by 2030. The achievement of this value is also directly affected by functioning of of health care system. In 2015, the United Nations, within the framework of the Sustainable Development Goals for the period up to 2030, formulated the task that implies ensuring of universal health services coverage "including financial risk security, access to qualitative essential medical and sanitary services and access to safe, effective, qualitative and inexpensive essential medications and vaccines for all".

[The medical demographic indicators and health preservation of rural population of the Russian Federation].

For the last 20 years of analysis, mortality rate of rural population was higher than that one of entire population; in 2020, increasing of mortality due to COVID-19 was noted.The indicators were 15.4 per 1000 population for rural population, and 14.

[The molecular genetic aspects of basal cell carcinoma from the position of population health preservation].

The exploration of molecular genetic mechanisms that underlie carcinogenesis, hereditary factors of various oncological diseases, including basal cell carcinoma, the most common type of skin cancer is especially actual and significant for target strategies of public health. The diagnosis of basal cell carcinoma is based on complex clinical, radiologic and genetic examination data. The further research in the field of somatic or hereditary mutations in genes associated with basal cell carcinoma, including Patched 1 (PTCH1), Patched 2 (PTCH2), Smoothed (SMO) continue to be topical.

[The social genetic aspects of higher prevalence and prevention of basal cell carcinoma].

The maintenance of health of residents of the Northern Regions of Russia, including those living in the Arctic zone of the cbountry, is a condition of its advance development in XXI century. The percentage of Russian citizen vaccinated against the new coronavirus infection (COVID-19) does not exceed 50% after beginning of implementation of vaccination program. It can be conditioned by lower level of both of credence of citizen to health care system and health literacy.

[The results of analysis of morbidity and mortality of population in conditions of COVID-19 pandemic].

The COVID-19 pandemic has its own objective features associated with density of residence, organization and accessibility of medical care, migration characteristics of population, etc. Therefore, analysis of current situation with coronavirus in the Russian Federation, its Federal Okrugs and subjects is needed. The coronavirus infection resulted in significant changes in indicators of primary morbidity and mortality of population of the Russian Federation.

[The medicinal support in ambulatory conditions and the integral estimates of public health].

Within the framework of the 2030 Agenda for Sustainable Development, goals were formulated, including those targeting to improve quality of life of people all around the world. The task was formulated to ensure universal coverage of health services. In 2019, the United Nations General Assembly noted that at least half of world's population have no access to basic health services.

[The algorithm of planning the needs in medical care provided in out-patient conditions to elderly age groups of population using mathematical models].

The purpose of the study is to develop algorithm for planning the need in medical care provided in out-patient conditions to elderly groups of population based on mathematical modeling methods. Research materials and methods. As a source of information, data on cases of medical care provided to the population of elderly age groups (60 years and older) were used.

[The medicinal support in palliative medical care: The review of normative legal acts].

The every patient, receiving palliative medical care, in case of pain syndrome requires specified medicinal therapy often with prescription of narcotic analgesics. The WHO developed the model lists of essential medications (differentiated for adults and children), including both drugs for treatment of the most symptoms in palliative care support and analgesics. The article presents the results of analysis of normative legal acts regulating medication support of citizens of the Russian Federation in case of palliative medical care applying both drugs treating main manifestations of diseases and arresting pain syndrome.

[The modern methods of evaluation of implementing personalized programs of prevention of age-associated diseases].

The development of preventive programs targeting specific groups of consumers of medical social services having age-related health and lifestyle characteristics is one of the most prospective methods to improve quality of medical care of the elderly and senile patients. The previously developed by Russian and foreign scientists programs of personalized prevention of age-related diseases make it possible to organize target groups of patients seeking medical services in both state and private health care organizations to be screened for conditions of medical and social significance from the point of view of preventive medicine. This permits to achieve a real integration of various components of preventive care that improves health of elderly and senile patients in terms of morphofunctional indices of patient's physical status, quality of life, degree of independence, and, as a result, quality and scope of implementation of preventive programs for elderly population.

[The methodology of controllable medical pharmaceutical monitoring of patients: from theory to practice (publications review)].

The preservation and promotion of health of citizens is largely determined by professional activity of both medical and pharmaceutical workers, as well as their coordinated interaction with active involvement of patient that confirms the relevance of research on improving organizational technologies for medical and pharmaceutical care of patients. The article presents an overview of international experience of controllable medical and pharmaceutical care of patient. The main interdisciplinary collaboration concepts of medical and pharmaceutical specialists from the point of view of patient health preservation is described.

[The analysis of health condition of individuals aged 40 years and older and going in for sports].

The attitude to high physical loads on organism in the middle and older age groups is ambiguous, from optimistic to completely pessimistic, associated with possibility of development pathological processes because of high physical activity. The purpose of the study is to evaluate health status of people aged 40 years and older involved in sports. The health data was obtained through interviewing athletes aged 40 years and older competing in track and field events at distances of 10 kilometers or more.

[The characteristics of population mortality of the Russian Federation, the Central Federal Okrug and City of Moscow in 2020].

To preserve the country's population is among one of the most vital tasks over the period of existence of the new Russia and constitutes the subject of national security. The article presents the results of analysis of population mortality rate of the Russian Federation, the Central Federal Okrug and City of Moscow during the first eight months of 2020 towards to concurrent period of 2019. In January-March 2020, the population total mortality rate, retaining prevalent trends of number of preceding years, decreased in the Russian Federation by 3.

[The organizational aspects of security support of participants of clinical testing of vaccine "Gam-COVID-Vac"].

The COVID-19 pandemic resulted in many aftermaths, economic crisis and extra charging of health care. The development of vaccine against SARS-nCoV-2 agent turned out as the priority task of world and Russian medicine and pharmaceutics. The investigation of efficiency and safety of vaccines can be prolonged for many years that can aggravate the observed crisis.

[The analysis of instruments of evaluation of quality of life of patients of elderly age in view of palliative medicine].

In quality of life research, it is very important to understand the concept and methodology of its implementation. The quality of life study should be organized in accordance with standard generally accepted requirements. In order to obtain comparable data and to apply it in clinical practice, standard quality of life assessment tools should be implemented.

[The analysis of indices of population morbidity at the level of region].

The article presents the results of the analysis of indices of morbidity of children and adults in the Kostroma Oblast in 2000-2017. The main trends and changes during analyzed period are established. The high morbidity in such classes of diseases as respiratory diseases, injuries and poisoning, complications of pregnancy, childbirth and postpartum period are determined.

[The complex evaluation of target indices population health in the Central Federal Okrug of the Russian Federation].

The article presents the results of analysis of values and dynamics of changes in indicators of fertility rate, expected life expectancy, total and infant mortality, able-bodied mortality, mortality of circulatory system diseases, neoplasms, and road traffic accidents in 18 subjects of the Central Federal Okrug of the Russian Federation in 2015-2018. The results of comparative analysis of factual values of mentioned indicators with values of target indicators approved by the "Health care Development Strategy in the Russian Federation for period up to 2025" (2019) are presented. The necessary scope of correction of existing discrepancies are established.

[The organizational aspects of early diagnostic of metabolic syndrome on the basis of implementation of new genetic, cellular and bio-informational technologies].

The characteristic feature of molecular medicine as medicine based on molecular structure of human genome data, is its individual character. It is focused on correcting pathological process in specific individual considering unique characteristics of its genome. The other most important feature is its expressed preventive direction.

[The contribution of the N. A. Semashko National Research Institute of Public Health into development of science and public health].

The article is devoted to the history of the creation and activities of the N. A. Semashko National Research Institute of Public Health.

[The Morbidity of Infection Diseases in the USSR: Myths and Reality. Report II. 1950-1990].

The article considers the made known, systematized and analyzed indices of morbidity of infectious diseases in the USSR in 1950-1990. The results of comparative analysis of morbidity of infectious diseases in the USSR and developed countries are presented. It is proved that despite of current opinion presented in publications epidemiological morbidity in the USSR was not eradicated.

[N.A. Semashko, the First People's Commissar of Health Care].

The article is devoted to 100th anniversary of organization of the Narkomzdrav of the Russian Soviet Federal Socialist Republic. The input of N.A.

[The Problems of Socially Dangerous Acts of Medical Workers in Sphere of Biomedical Technologies].

The complex problem is considered related to socially dangerous acts of medical workers in the sphere of biomedical technologies covering, besides "traditional" iatrogenic crimes, other risks of application of the mentioned technologies for criminal purposes. The study uses the results of original observations and theoretical findings and data of information content analysis of 2012-1017, data of analysis of medical and judicial practice and also result of sociological survey of experts-medical workers of various profiles professionally related to application of biomedical technologies (n=278). The social legal status of medical worker conditions a potential possibility of application of corresponding abilities, skills, competences, official position and authority to commit crimes in the sphere of their professional activities.