[Activity of the messenger systems in the altitude chamber hypoxia].

The activity of phosphoinositide and adenylate cyclase systems of second messengers in rat brain were investigated under altitude chamber treatment (6000 m x 24 hours). Selective suppression of each messenger system was achieved by pretreatment of rats with either lithium chloride or propranolol for 8 days. Consequences of this treatment and/or hypoxia were evaluated by orientation behavior and physical exercise test.

[Study of molecular damage in bronchial asthma and cerebrovascular disorders during the course of rehabilitation ].

Drug treatment of cerebrovascular disorders alone and in combination with UV irradiation of autoblood gave rise to a positive trend in clinical and functional parameters more noticeable in the combined treatment. Also, there was a fall in red cell levels of malonic dialdehyde. A course of speleotherapy given to children with bronchial asthma contributed to normalization of free radical oxidation and reestablishment of molecular structure in red cell membranes.