Publications by authors named "Kh Khristov"

An epidemiological study on the wide spreading of nosocomial infections among patients admitted to intensive care units in Bulgaria is carried out, covering the period 1982 through 1996. The proportion of nosocomial infections registered in the aforementioned wards accounts for 4.66 +/- 0.

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The wide-spreading of intrahospital infections in urological departments on a nationwide scale are analyzed over the period 1982 through 1996. Their epidemiological, etiological and nosological characterization is also defined. In this country over 6 per cent of all hospital infections occur in urological departments.

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The epidemiologic, etiologic and clinical structure of HAI in the maternity and neonatal wards in the country for the 1982-1992 period has been specified. 934 women in child-birth and 2357 neonates acquire nosocomial infections at an average annually. A comparatively constant level in HAI epidemic process intensity is observed with inconsiderable diversions in the beginning and by the end of the studied period.

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The clinical course, diagnosis and treatment of Peutz--Jeghers's syndrome in childhood are discussed and a case reported in a eight-year-old girl. The disease presented with skin and mucosal melanin pigmentation in the mouth, frequent colic-like abdominal pain, due to chronic recurrent invaginations. On operation, the cause of the invaginations appeared to be 11 polypous formations in small intestines (8) and in the large intestines (3), which were subjected to radical operative removal.

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The authors analyse the results of surgical treatment of 316 patients with peptic ulcer after gastric resection completed by the formation of terminolateral gastroduodenoanastomosis after the Haberer-Finney techniques. In 189 patients vagotomy was carried out in addition to the operation. The postoperative mortality rate was 0.

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One of the rare surgical diseases of the organs in the abdominal cavity in children are the splenic cysts. For a period of 20 years (1968-1988) 3 children have been observed and treated at the Clinic of Pediatric Surgery in Sofia. The use of modern diagnostic methods--echography, computer axial tomography, scintigraphy and laparoscopy furnished an opportunity for precise preoperative organ localization of the disease in the patients observed by the authors.

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In a series of 4350 children with abdominal surgical diseases operated at the Department of Pediatric Surgery in Sofia for a period of 3 years (1987-1989) the authors have observed 4 cases of pleuropulmonary complications (0.09 per cent). In two of these children the primary abdominal operation was for liver echinococcus, in 1--rupture of the liver and subphrenic abscess and in 1--perforative appendicitis and purulent peritonitis.

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Two cases of primary tumors of the stomach in children (7 and 10 years of age) are reported. One of them had non-Hodgkin's lymphoma and the other hamartoma, both radically operated. In the former case subtotal resection of the stomach was made followed by polychemotherapy.

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The combination of subphrenic abscess with purulent pericarditis is a rare postoperative complication of perforated appendicitis in children, with severe clinical course, difficult to diagnose and high case fatality rate. A 7-year-old child with this complication, successfully diagnosed and treated is reported. The importance of complex therapy--surgical and intensive and collaboration between pediatric surgeons, anesthesiologists, cardiac surgeons and cardiologists for the favourable outcome is emphasized.

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The aim of the study is to follow up the changes in auditory and vestibular systems, common interactions between the sensory systems and the changes in some biochemical indices after vestibular loading in drivers. Several groups of drivers of heavy freight trucks were studied, aged from 25-60 and a length of service from 5 to 30 years, according to a standard programme for otoneurological examination and application of modern otoneurological methods. The biochemical investigations were performed to 32 healthy and 19 sick drivers with vestibular disorders, prior to and post vestibular provocation.

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The epizootiology of Salmonella infections in swine was studied in 1970-1980 in 7 districts of this country on a number of farms and industrial complexes in order to elucidate some aspects of the epizootiologic process. A total of 26,957 samples taken from swine and the environment were studied bacteriologically. An industrial complex in each district served as a test one to investigate samples from various groups of swine in the technologic process.

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A total of 25,114 samples taken from fetuses, pigs, adult swine, feces, environmental objects, etc. in 6 regions of this country were studied bacteriologically in 1976-1980, and in 1970-1975 a retrospective analysis was made of data of investigations with pigs in the same regions. The sample study led to the isolation of 1,495 strains of 21 Salmonella species of the B, C, D, and E groups.

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A case is described with incomplete syndrome of Hutchinson-Gilford in a male, aged 29. The development of the disease in the patient was followed-up. The pathologoanatomical changes, observed in the patient were described.

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A complex study was carried out on the vestibular disorders in 60 transport workers with cervical osteochondrosis in order to determine their incidence and character. The workers' age was from 20 to 60 and a length of service as drivers of transport vehicles - from 3 to 16 and even more years. The vestibular system was studied with regard to spontaneous nystagmic manifestations, the state of stato-kinetics, via experimental rotation and caloric provocations.

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