Publications by authors named "Kfir Tal"
Identification and Characterization of a Non-muscular Myostatin in the Nile Tilapia.
Front Endocrinol (Lausanne)
March 2021
The growth and differentiation factor Myostatin (MSTN, also known as GDF8) negatively regulates skeletal muscle development and growth in vertebrates. Most fish genomes contain two or more genes, which are expressed in muscle and other tissues. Yet, in the genome of Nile tilapia (), which is one of the world's most important aquaculture fish species, only one gene has previously been identified.
View Article and Find Full Text PDFPurpose: To determine whether intravitreal unconjugated tissue plasminogen activator (tPA) (alteplase) can penetrate the intact neural retina and reach the subretinal space in an experimental model.
Methods: This study was performed in 24 Sprague-Dawley rats aged 12 weeks. Under general anesthesia, the right eye was injected with either 0.
Antivascular endothelial growth factor (Anti-VEGF) agents have been widely used for a variety of ocular disorders. The etiology of sustained ocular hypertension following intravitreal administration of anti-VEGF agents is yet to be unraveled. Our study investigates and characterizes the presence of intravitreally injected bevacizumab in the aqueous outflow channels of a rat model.
View Article and Find Full Text PDFPurpose: To evaluate the efficacy of corneal collagen cross-linking (CXL) with photoactivated riboflavin (PACK-CXL) as primary therapy for Staphylococcus aureus-induced corneal ulcers in a rabbit model.
Methods: The right eye of 40 rabbits was inoculated with S. aureus to induce formation of central corneal ulcers (day 1).
We aimed to evaluate the effectiveness of temperature-controlled laser soldering for repair of large perforated corneas in a porcine model. Eight Yorkshire pigs aged 6 months underwent 6-mm-deep 180° crescent-shaped trephination of the central corneas. Right corneal injuries were repaired by placement of 47 % bovine albumin along the cut followed by CO2 laser soldering (power density 16 W/cm(2)) to a target temperature of 65(°).
View Article and Find Full Text PDFArticle Synopsis
- Mechanical load helps bones and growth plates develop, and a part of the cell called the primary cilium helps cells sense this load.
- The primary cilium plays a role in important processes like how cells grow and change shape in the growth plate.
- The study found that when there is more mechanical load, it increases the number of primary cilia, which affects how the cells grow and develop, leading to some problems with their organization and shape.
Background And Objective: To evaluate the protective effect of different ophthalmic viscosurgical devices (OVDs) on corneal endothelial cells against relatively severe phacoemulsification damage in a rabbit model.
Materials And Methods: Twenty-four rabbit eyes were randomly assigned to four similar groups: in three groups the aqueous humor was completely replaced by Visiol (TRB CHEMEDICA, München, Germany), Biolon (Bio-Technology General Ltd., Kiryat Malachi, Israel), and Viscoat (Alcon, Puurs, Belgium) and in the control group no OVD was applied.
Purpose: To evaluate the protective effect of different ophthalmic viscosurgical devices on corneal endothelial cells during phacoemulsification in a rabbit model.
Setting: Harlan Biotech Israel and Ophthalmology Department, Kaplan Medical Center, Rehovot, Israel.
Design: Experimental study.