Publications by authors named "Keyue Pan"
Article Synopsis
- Ischemic post-conditioning (I-post C) is a method used to protect lung tissue from damage due to ischemia/reperfusion injury, but the exact mechanisms behind its protective effects are not well understood.
- The study utilized RNA sequencing and various analyses to explore differentially expressed genes (DEGs) in rat lung tissues after treatment with I-post C, identifying significant pathways associated with inflammation and lung protection.
- Results showed that I-post C reduced lung edema and inflammation, with 38 DEGs identified, including key molecules in inflammatory response and signaling pathways, notably downregulating certain inflammatory markers and pathways involved in neutrophil activation.
Objectives: Serum lactate and creatinine levels upon admission in cardiac arrest (CA) patients significantly correlate with acute kidney injury (AKI) post-restoration of autonomic circulation. However, the association between serum lactate/creatinine ratio (LCR) and AKI in this population remains unclear. This study aimed to explore the relationship between LCR at admission and cardiac arrest-associated acute kidney injury (CA-AKI).
View Article and Find Full Text PDF[Predictive value of sequential organ failure assessment on 28-day mortality in patients with post-cardiac arrest syndrome].
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
December 2022
Objective: To evaluate the predictive value of sequential organ failure assessment (SOFA) for 28-day mortality in patients with post-cardiac arrest syndrome (PCAS).
Methods: Retrospective analysis of 125 patients with PCAS who were treated in Emergency Intensive Care Unit (EICU) of Wenzhou People's Hospital from July 2016 to July 2021. Clinical data were collected, including age, gender, underlying diseases, acute physiology and chronic health evaluation II (APACHE II), SOFA score on admission to EICU and 28-day mortality.