Publications by authors named "Keying Bi"
Cardiac light-chain amyloidosis (AL-CA), characterized by the accumulation of amyloid fibers in the myocardium, often results in progressive diastolic dysfunction and adverse clinical outcomes. This study aimed to explore the diastolic characteristics of AL-CA using feature tracking cardiac magnetic resonance (CMR) and determine the prognostic parameters for all-cause mortality in such patients. A total of 102 AL-CA patients who underwent CMR between January 2014 and September 2018 were retrospectively reviewed, participations were follow-up until 2021.
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- The study assessed the prognostic value of the left atrioventricular coupling index (LACI) in predicting all-cause mortality in patients with light-chain amyloidosis (AL).
- A total of 179 patients were analyzed, with results showing that a higher LACI was linked to increased mortality; specifically, a cut-off of 49.3% for LACI was identified as a significant predictor.
- The findings suggest that LACI can serve as an additional biomarker for risk stratification in advanced stages of AL amyloidosis, enhancing prediction accuracy beyond just the Mayo stage.
Background: First-pass perfusion cardiac MR imaging could reflect pulmonary hemodynamics. However, the clinical value of pulmonary transit time (PTT) derived from first-pass perfusion MRI in light-chain (AL) amyloidosis requires further evaluation.
Purpose: To assess the clinical and prognostic value of PTT in patients with AL amyloidosis.