Publications by authors named "Keyhan R Ghahfarouki"
Oral Nano-Curcumin in a Model of Chronic Gulf War Illness Alleviates Brain Dysfunction with Modulation of Oxidative Stress, Mitochondrial Function, Neuroinflammation, Neurogenesis, and Gene Expression.
Sahithi Attaluri Meenakshi Arora Leelavathi N Madhu Maheedhar Kodali Bing Shuai Keyhan R Ghahfarouki
Aging Dis
April 2022
Article Synopsis
- Chronic Gulf War Illness (GWI) is linked to cognitive and mood issues, oxidative stress, and neuroinflammation, creating significant health challenges for veterans.
- The study explored the use of low-dose, oral polymer nanoparticle-encapsulated curcumin (nCUR) to enhance brain function in a rat model of GWI, showing promising results in reducing brain dysfunction.
- Treatment with nCUR led to improved cognitive and mood functions, enhanced mitochondrial performance, reduced neuroinflammation, and promoted neurogenesis, suggesting potential benefits for veterans suffering from GWI.