Publications by authors named "Kexin Guo"
Natural polymer hydrogels, such as pullulan-based hydrogels, offer significant advantages over synthetic materials due to their thermal stability, film-forming capacity, solubility, adhesiveness, and antioxidant properties. In this study, the strain Aureobasidium melanogenum TZ-FC3, which produces a high level of pullulan, was successfully isolated from the mangrove ecosystems of Guangdong Province, China. 66.
View Article and Find Full Text PDFAn integrated path differential absorption (IPDA) lidar for CH leakage monitoring is proposed and demonstrated. In the simplified all-fiber optical layout, a homemade InGaAs/InP single-photon detector (SPD) using multi-channel technique with multi-mode fiber coupling is used to increase the maximum count rate and coupling efficiency. The system is calibrated in intensity and frequency domains.
View Article and Find Full Text PDFBackground: There is growing evidence that atrial fibrillation (AF) is a risk factor for cognitive impairment (CI) and dementia in the presence or absence of stroke. The purpose of this study was to explore the mechanism of CI caused by AF.
Methods: Eighteen male canines were randomly divided into a sham group, a pacing group, and a pacing + GW4869 group.
Novel magnetic adsorbents based on oyster and clam shells for the removal of cadmium in soil.
Sci Total Environ
December 2024
Magnetic adsorbents can effectively remove heavy metals from soil. However, the magnetization process may reduce availability of adsorption sites, making it challenging to balance magnetic and adsorption properties. In this study, oyster shell (OS) and clam shell (CS) material was magnetized by an improved chemical co-precipitation method.
View Article and Find Full Text PDFBackground: The relationship between local epicardial adipose tissue (EAT) macrophages and atrial fibrillation (AF) remains unclear. The purpose of this study was to investigate the role of K3.1 in the migration of macrophages from EAT to adjacent atrial tissue during rapid pacing.
View Article and Find Full Text PDFBackground: Pediatric patients with intestinal failure require long-term parenteral nutrition owing to impaired enteral nutrition absorption. A potential complication is essential fatty acid deficiency (EFAD), resulting from decreased linoleic and α-linolenic acid concentrations and defined by an increased triene:tetraene ratio (TTR; Mead acid:arachidonic acid). Historically, soybean oil lipid emulsion (SOLE) was the only commercially available parenteral lipid in the United States.
View Article and Find Full Text PDFArticle Synopsis
- * A systematic review of literature identified 21 studies that show PBL is widely adopted and effective for improving critical thinking and teamwork, but it faces challenges like faculty resistance and resource shortages.
- * To successfully implement PBL in China, it's important to provide proper training for faculty, create effective assessment methods, and establish supportive environments for collaborative learning.
Article Synopsis
- - Omadacycline and eravacycline are new tetracycline antibiotics being used against Gram-negative bacteria, but resistance has been reported due to tetracycline-inactivating enzymes.
- - A resistance strain with the mobile tigecycline resistance gene (X4) was isolated from a patient in Zhejiang, China, showing high resistance levels to eravacycline and omadacycline.
- - The study emphasizes the role of the (X4) gene on a plasmid in contributing to antibiotic resistance and highlights the need for ongoing monitoring to control its spread in China.
Article Synopsis
- Fibroblast-derived exosomes are shown to play a role in regulating heart cell electrical activity, particularly through the intermediate-conductance calcium-activated potassium channel (KCa3.1), which is involved in atrial electrical remodeling.
- The study involved isolating heart cells from rats and using electrical stimulation to create a model of atrial fibrillation, with experiments designed to see how exosomes from fibroblasts influenced KCa3.1 and related mechanisms.
- Findings indicated that increased exosome secretion during rapid heart pacing enhanced KCa3.1 expression and altered heart cell action potentials, while blocking KCa3.1 reduced action potential duration and potentially the risk of atrial fibrillation.
Article Synopsis
- A new method was created to synthesize allylic sulfones from allylic alcohols and sulfonyl hydrazines using a mild process in water.
- The process utilizes the commercially available catalyst Pd(PPh) and operates effectively at 40 °C in the presence of air.
- This approach eliminates the need for nitrogen protection and organic solvents, making it easy to scale up for larger quantities, enhancing its practical applications.
A 1.57-µm coherent differential absorption lidar is demonstrated for measuring three-dimensional CO and wind fields simultaneously. The maximum detection range of CO is up to 6 km with a range resolution of 120 m and a time resolution of 1 min.
View Article and Find Full Text PDFEmergence of an Extensive Drug Resistant Clinical Strain Harboring , , and .
Infect Drug Resist
June 2024
Background: To explore the plasmid characteristics and transfer mechanisms of an extensive drug resistant (XDR) clinical isolate, L2724hy, co-producing , , and .
Methods: Species confirmation of L2724hy was achieved through 16S rRNA sequencing and Average Nucleotide Identity (ANI) analysis. Antimicrobial susceptibility testing (AST) employed the agar dilution and micro broth dilution methods.
Article Synopsis
- - *Ichthyosis is a diverse skin disorder with different types, notably autosomal recessive congenital ichthyosis (ARCI), which can cause various skin phenotypes, especially due to mutations in the ABCA12 gene.* - *A patient diagnosed with congenital ichthyosiform erythroderma (CIE) had two rare ABCA12 mutations identified, impacting mRNA splicing and protein integrity, which were linked to his condition through genetic analysis.* - *Findings from this study not only highlight the specific variants responsible for the patient’s phenotype but also enhance understanding of ABCA12-related disorders, aiding in future genetic counseling and prenatal diagnosis.*
MoS/ReS Hollow Heterojunction for Enhanced Aqueous Zinc-Ion Storage Performance.
ACS Appl Mater Interfaces
April 2024
Article Synopsis
- Research on cathode materials for water-based zinc ion batteries (ZIBs) is critical due to current electrodes' limitations in achieving high discharge capacity and structural stability during electrochemical processes.
- This study introduces hollow bimetallic heterojunction nanospheres created through a simple hydrothermal method, which demonstrate impressive electrochemical properties, including high-rate performance and stable cycling.
- The findings suggest that these nanospheres support material structure and enhance Zn migration, thanks to abundant active sites and improved electron mobility, potentially expanding the application range of ZIBs through various modification strategies.
Article Synopsis
- Cadmium (Cd) in soil poses health risks as it can enter the food chain through crops, prompting a study on how silicate and phosphate amendments affect this transfer in leafy vegetables, specifically pak choi.
- The research utilized various treatment groups of contaminated soil to assess the effectiveness of different immobilizing agents (wollastonite, potassium tripolyphosphate, and sodium hexametaphosphate) in reducing Cd levels and its bioaccessibility in the plants.
- Results showed that while wollastonite alone increased Cd in pak choi, combining it with phosphates significantly reduced bio-Cd levels by up to 66.13%, suggesting these amendments can aid in phytoremediation of mildly contaminated soils.
Article Synopsis
- - Plant leaves exhibit diverse shapes due to their ability to respond to environmental changes, sparking interest in both scientific research and engineering applications.
- - This study investigates the mechanics of leaf folding caused by differential shrinking during dehydration, revealing a correlation between folding angles and water loss, and developing a model for this relationship.
- - By exploring the structural features responsible for leaf deformation, the research leads to the creation of biomimetic devices like humidity sensors that mimic natural folding processes, enhancing our understanding of plant-water interactions and informing soft machine design.
Poor management and excess fertilization of apple (Malus domestica Borkh.) orchards are causing increasingly serious soil acidification, resulting in Al toxicity and direct poisoning of roots. Strigolactones (SLs) are reported to be involved in plant responses to abiotic stress, but their role and mechanism under AlCl stress remain unknown.
View Article and Find Full Text PDFBackground: Norovirus (NoV) can cause chronic relapsing and remitting diarrhea in immunocompromised patients. Few multicenter studies have described the clinical course, outcomes, and complications of chronic NoV in transplant recipients.
Methods: A multicenter retrospective study of adult and pediatric SOT and HSCT recipients diagnosed with NoV between November 1, 2017, and February 28, 2021.
Article Synopsis
- Environmentally adaptive hydrogels can change shape in response to external stimuli, showing promise for applications in soft robotics and bioinspired actuation.
- Past research has mostly focused on complicated designs or stimuli, making it tough to achieve self-regulating shape changes in uniform hydrogels.
- This study introduces a new type of homogeneous hydrogel that uses two spiropyrans to enable reversible shape transformations when exposed to constant light, allowing for innovative programming of complex movements.
Article Synopsis
- A study was conducted to analyze strabismus surgery patterns in a Central China hospital during the COVID-19 pandemic, focusing on data from January 2020 to December 2022.
- A total of 3,939 surgeries were performed, with significant decreases noted in February 2020, August 2021, and late 2022, while 37% of patients were aged 0-6 years.
- The majority of patients had exotropia (60%), with intermittent exotropia being the most common subtype; there were no significant changes in the prevalence of intermittent vs. constant exotropia over the study period.
Hemifacial spasm (HFS) is a rare movement disorder characterized by involuntary muscle contractions on one side of the face. Compared to the high therapeutic effect, adverse effects of botulinum toxin treatment for HFS occurred rarely. However, managing HFS patients who are also taking antithrombotic drugs poses a challenge.
View Article and Find Full Text PDFBackground: Frailty is prevalent in patients with end-stage liver disease and predicts waitlist mortality, posttransplant mortality, and frequency of hospitalizations. The Liver Frailty Index (LFI) is a validated measure of frailty in liver transplant (LT) candidates but requires an in-person assessment.
Methods: We studied the association between patient-reported physical function and LFI in a single-center prospective study of adult patients with cirrhosis undergoing LT evaluation from October 2020 to December 2021.