Publications by authors named "Kewei Gao"

Biodegradable Zn-0.4Li alloys have been considered as medical implants due to their excellent mechanical properties and desirable biocompatibility. In this work, anodization was applied to modified corrosion resistance of the Zn-0.

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Background And Aim: Long non-coding RNAs (lncRNAs) play an important role in tumor progression, including in hepatocellular carcinoma (HCC) induced by hepatitis B virus (HBV). Therefore, the aim of this study was to investigate the role of LINC02532 in HCC, mainly for diagnostic prognostic value and cellular function, as well as mechanistic aspects.

Methods: Initially, GEO and VirBase databases were used to screen for aberrant lncRNAs in HBV-HCC.

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Article Synopsis
  • This study explored the effects of chrysophanol, a compound, on inducing programmed cell death (apoptosis and ferroptosis) in gastric cancer cells.
  • Results showed that while chrysophanol had no harmful effects on normal gastric cells (GES-1), it significantly inhibited colony formation and proliferation of cancer cells at concentrations above 25 μM.
  • The research suggested that chrysophanol works through mechanisms involving the mitochondrial membrane potential, reactive oxygen species, and regulation of the mTOR signaling pathway, highlighting its potential as a treatment for gastric cancer.
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Weathering steel, which has a protective corrosion product film, is widely used in various construction and landscaping applications. However, it causes metal contamination in the receiving ecosystem via corrosion-induced metal dissolution and rust runoff. Traditional corrosion prevention methods, such as surface coating, also suffer from environmental pollution and high maintenance costs.

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A strategy for optimizing the rolling resistance, wet skid and cut resistance of reinforced rubber simultaneously using a supramolecular filler is demonstrated. A β-alanine trimer-grafted Styrene Butadiene Rubber (A-SBR) pristine polymer was designed and mechanically mixed with commercially available styrene butadiene rubber to help the dispersion of a β-alanine trimer (A) supramolecular filler in the rubber matrix. To increase the miscibility of A-SBR with other rubber components during mechanical mixing, the pristine polymer was saturated with ethanol before mixing.

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The empirical modeling methods are widely used in corrosion behavior analysis. But due to the limited regression ability of conventional algorithms, modeling objects are often limited to individual factors and specific environments. This study proposed a modeling method based on machine learning to simulate the marine atmospheric corrosion behavior of low-alloy steels.

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Cirrhosis and portal hypertension are associated with an increased risk of developing liver cancer. However, it is unknown how changes in the cellular mechanical microenvironment induced by portal hypertension affect the occurrence and development of liver cancer. The aim of this study was to determine the effect of tensile strain on the proliferation of a human liver cancer cell line (HepG2 cells) using methods such as flow cytometry, Cell Counting Kit‑8 and 5‑bromodeoxyuridine assays, and to examine the changes in microRNA (miRNA/miR) expression using microarray, reverse transcription‑quantitative (RT‑q)PCR and bioinformatics analyses.

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Mechanical pressure may contribute to the development of cancer; however, there is currently no evidence regarding the effect of mechanical pressure on liver cancer. In the present study, 2‑ and 3‑dimensional pressure‑loading systems were used to exert pressure on HepG2 and Huh‑7 cell lines. Cell proliferation and flow cytometry analyses were undertaken to observe the proliferative ability of pressure‑loaded cells.

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As an effective and environmentally friendly material for corrosion prevention, layered double hydroxide (LDH) films have usually been degraded due to their inherent microporous structure. In this study, graphene derivatives were employed to enhance the corrosion resistance of LDH films. After ultrasonic treatment of a reaction solution mixture containing graphene oxide (GO) powder, a reduced graphene oxide/zinc-aluminum LDH (RGO/Zn-Al LDH) film was in situ synthesized on a magnesium alloy substrate by a one-step facile hydrothermal crystallization process.

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The olfactory evaluation function (e.g., odor intensity rating) of e-nose is always one of the most challenging issues in researches about odor pollution monitoring.

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Landfills have been widely constructed all around the world in order to properly dispose municipal solid waste (MSW). Understanding geotechnical properties of MSW is essential for the design and operation of landfills. A comprehensive investigation of geotechnical properties of MSW at the largest landfill in China was conducted, including waste composition, unit weight, void ratio, water content, hydraulic conductivity, and shear behavior.

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The preferred growth orientation of the sputtered lead selenide (PbSe) thin films on Si(100) substrates was thermodynamically simulated and calculated on the basis of the density functional theory. The results showed that the total free energy variation during the grain growth is dominated by the interface and strain energy minimization under certain conditions, indicating that the preferred growth orientation and related optical properties of the PbSe thin films can be effectively modified by these two energy variations. Thermodynamically, the PbSe[200] and PbSe[220] preferred orientations are obtained when the interface and strain energy minimization dominate the total free energy variation, respectively.

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Background: Circulating microRNAs (miRNAs) are emerging as promising biomarkers for human cancer. Osteosarcoma is the most common human primary malignant bone tumor in children and young adults. The objective of this study was to investigate whether circulating miRNAs in plasma could be a useful biomarker for detecting osteosarcoma and monitoring tumor removal dynamics.

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