Proc Natl Acad Sci U S A
July 2021
A significant unmet need for new contraceptive options for both women and men remains due to side-effect profiles, medical concerns, and the inconvenience of many currently available contraceptive products. Unfortunately, the development of novel nonsteroidal female contraceptive medicine has been stalled in the last couple of decades due to the lack of effective screening platforms. utilizes conserved signaling pathways for follicle rupture, a final step in ovulation that is essential for female reproduction.
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