Publications by authors named "Kevin W Dwyer"

Article Synopsis
  • Periprosthetic joint infection (PJI) diagnosis after total knee arthroplasty is complicated, with next-generation sequencing (NGS) being more sensitive but less specific and more costly than traditional culture techniques.
  • A Markov model was used to assess the cost-effectiveness of these diagnostic methods, indicating that culture is not cost-effective compared to NGS, which becomes more favorable at higher probabilities of PJI.
  • NGS's cost-effectiveness heavily relies on the likelihood of PJI occurring beforehand, suggesting it is best used in situations with high pretest probability; more research is needed to clarify when NGS provides the most benefit.
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Fat embolism syndrome (FES) is most commonly diagnosed when the classic triad of respiratory difficulty, neurologic abnormalities, and petechial rash are present in the appropriate clinical setting. Neurologic manifestations can range from headache, confusion, and agitation to stupor and, less commonly, coma. This article describes a case of FES with severe neurologic sequelae without typical pulmonary involvement in a polytrauma patient with proximal humerus and L1 compression fractures.

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