Publications by authors named "Kevin S Guo"
Article Synopsis
- The study investigates how comorbidities affect the occurrence of immediate post-operative complications in patients who had oral cavity composite resection with free flap reconstruction.
- Data was gathered from 320 patients treated from 1999 to 2020, revealing that 37.8% experienced post-operative complications, with common issues being cardiopulmonary events, pneumonia, and wound infections.
- Patients without comorbidities were less likely to face complications, while conditions like atrial fibrillation and cerebrovascular disease significantly increased the risk of complications, particularly pneumonia.
The extracellular matrix (ECM) is a critical determinant of tumor fate that reflects the output from myriad cell types in the tumor. Collagens constitute the principal components of the tumor ECM. The changing collagen composition in tumors along with their impact on patient outcomes and possible biomarkers remains largely unknown.
View Article and Find Full Text PDFBackground: Gastric cancer is a heterogeneous disease with poorly understood genetic and microenvironmental factors. Mutations in collagen genes are associated with genetic diseases that compromise tissue integrity, but their role in tumor progression has not been extensively reported. Aberrant collagen expression has been long associated with malignant tumor growth, invasion, chemoresistance, and patient outcomes.
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