Occult breast cancer: scintimammography with high-resolution breast-specific gamma camera in women at high risk for breast cancer.

Purpose: To prospectively evaluate a high-resolution breast-specific gamma camera for depicting occult breast cancer in women at high risk for breast cancer but with normal mammographic and physical examination findings.

Materials And Methods: Institutional Review Board approval and informed consent were obtained. The study was HIPAA compliant.

Impact of breast density on computer-aided detection for breast cancer.

Objective: Our aim was to determine whether breast density affects the performance of a computer-aided detection (CAD) system for the detection of breast cancer.

Materials And Methods: Nine hundred six sequential mammographically detected breast cancers and 147 normal screening mammograms from 18 facilities were classified by mammographic density. BI-RADS 1 and 2 density cases were classified as nondense breasts; BI-RADS 3 and 4 density cases were classified as dense breasts.