Publications by authors named "Kevin Mahan"

Article Synopsis
  • The continental lithosphere holds the oldest stable structures on Earth, preserving fragments of ancient material that have survived billions of years of tectonic and surface processes.
  • Using uranium-lead thermochronology on volcanic rocks, researchers created a detailed record of how these ancient rocks have cooled and been uplifted, providing insights into the continents' physical properties and erosion forces over time.
  • The findings indicate that these ancient rocks have experienced very low erosion rates that have remained consistent over nearly the entire lifespan of the continents.
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Twenty analogues were synthesized of [Pmp1, D-Trp2, Arg8]oxytocin, PA, (Pmp = beta,beta-pentamethylene-beta-mercaptopropionic acid), a potent antagonist of the uterotonic effect of oxytocin in the rat (uterotonic test in vitro, pA2 = 7.77) and in the baboon. Systematic substitution of Pmp1 was made with beta-mercaptopropionic acids featuring replacement of the 4-methylene group of the cyclohexyl ring of Pmp with isosteric O, S, NH or with C=O.

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