Giant Appendicolith: A Case Report and Review of the Literature.

Acute appendicitis is one of the most prevalent causes of an acute abdomen. Although the cause of appendicitis is not completely understood, the theory of luminal obstruction is a popular belief, with appendicoliths being a common etiology. While appendicoliths are quite common, giant appendicoliths >2 cm are rare.

Duodenal Adenocarcinoma at the Ligament of Treitz: Management and Outcome.

Primary small bowel neoplasms at the ligament of Treitz are extremely rare and require advanced surgical technique for extirpation. The insidious onset of disease allows for a delayed presentation, often accompanied by moderate-size growth of the neoplasm, causing intestinal bleeding and bowel obstruction. The partial retroperitoneal location of these tumors pose a unique challenge for surgical resection.

Recurrent Inactive Hydatid Cyst of the Liver Causing Restrictive Pulmonary Physiology.

Hydatid and alveolar cysts are formed by the helminths and , respectively, which are endemic to pastoral areas, and are more commonly found in South America, the Mediterranean, Russia, and China. Hydatid cysts can cause bacteremia, form abscesses, or cause mass effect by compressing surrounding organs. Strategies to prevent such complications include benzimidazoles, surgical resection, and Puncture, Aspiration, Injection and Re-aspiration (PAIR) procedure.

Management of Symptomatic Hepatic "Mega" Hemangioma.

The majority of giant hepatic cavernous hemangiomas are asymptomatic and can safely be observed. However, when a lesion becomes symptomatic, affecting quality of life or cannot be distinguished from a malignancy, then operative therapy should be considered. We herein present a case of a symptomatic 12cm × 14cm × 17cm "mega" hemangioma (>10cm) of the left hepatic lobe.

Restoration of vaginal anatomy after extensive posterior wall resection utilizing human acellular dermal matrix.

• Pelvic tumor debulking encompassing the vaginal wall can preclude simple closure. • Current repair options that maintain sexual function and anatomy are limited. • This is the first published case of an acellular matrix used for such reconstruction.

Excess of extracolonic non-endometrial multiple primary cancers in MSH2 germline mutation carriers over MLH1.

Background: The lynch syndrome (LS) tumor spectrum involves colorectal cancer (CRC), endometrial cancer (EC), and less frequently various extracolonic non-endometrial cancers (non-EC). The organ-specific survival rates of these patients are well defined, however, the collective survival of all-cancers combined (CRC + EC + non-EC) are unclear.

Methods: Fifty-two MSH2 patients and 68 MLH1 patients were followed for a median of 6.

Infiltrating mammary carcinoma with osteoclast-like giant cells.

Mammary carcinoma with osteoclast-like giant cells is an uncommon variant. The following case examines a 36-year-old woman incidentally found to have a left breast mass on routine physical exam. Initial ultrasound-guided core biopsies revealed infiltrating mammary carcinoma with focal mucinous features, for which a left breast lumpectomy and sentinel lymph node biopsy were performed.

Hepatic hemangiomas and parachuting.

Hepatic hemangiomas are relatively common benign hepatic tumors. Historically, a concern for potential traumatic rupture has influenced clinical judgment regarding optimal treatment. However, a review of the literature fails to demonstrate spontaneous or traumatic rupture as a common phenomenon.